Given Cordycepin’s ability to downregulate NRP1 expression, it may warrant investigation as an adjunct therapy for Long COVID.
(Neuropilin 1 (NRP1) is a protein expressed by various cells in the body, including neurons, blood vessels, and immune cells. It binds to different types of extracellular ligands, influencing the development and functioning of organs. NRP1 is involved in signaling pathways, particularly in the brain and retina, and has potential as a target for therapeutics in the treatment of neovascular eye diseases.)
(A ligand is simply a molecule or ion that binds to a central entity—either a metal atom (in chemistry) or a receiving protein (in biology)—to form a larger complex. This binding triggers a specific chemical or physiological response.)
(In science, an ion is an atom or molecule that has a net electrical charge because it has gained or lost one or more electrons. Because they are electrically charged, ions play critical roles in everything from biological nerve impulses to battery technology.)
Finish reading: https://wmcresearch.substack.com/p/friday-hope-cordycepin-cd-from-the