Category: General Interest

A breached blood-brain barrier isn’t just a neurological inconvenience – it’s a direct pathway to fatal outcomes, and the mechanisms are well understood.

Just 59 views of this paper that should be front page news. The COVID vaccine, which causes your body to produce spike protein which disrupts the blood-brain barrier is unsafe by design should never have been put on the market.

Executive summary

The new Jmii paper, “SARS-CoV-2 disrupts the integrity of a human blood-brain barrier model in the absence of infection” is the latest confirmation that the spike protein generated from the COVID vaccine can dislodge the blood-brain barrier (BBB) which can lead to all sorts of temporary and/or permanent neurological injuries including death.

In short, the COVID vaccine is inherently unsafe by design.

Given to perfectly healthy people, it can leave you with permanent and severe neurological damage. Or dead.

This has happened to people who take the COVID shots and now we have further confirmation of the mechanism because the Jmii paper replicates other studies (one as early as 2020) and it also aligns with autopsy findings demonstrating vaccines breach of the BBB.

It’s a violation of medical ethics to give these shots, but it’s legal because they are FDA approved.

The COVID vaccines should be taken off the market. Now.

Finish reading: https://open.substack.com/pub/stevekirsch/p/jmii-paper-adds-to-the-evidence-that

I considered this then thought to find out what might help mitigate or reverse the vaccine induced harm. So I asked Grok, “You and I previously worked on a nutritional support formula to help a body with DNA/Heart/Mitochondrial support post COVID vaccines. I would like to investigate natural ingredients that help a body restore a properly functioning blood-brain barrier. What data can you provide on that?”

Grok replied:
On restoring a properly functioning blood-brain barrier (BBB), note upfront that there are no established, clinically proven natural supplements or foods that reliably “repair” a BBB breached by spike protein or vaccination in humans. BBB integrity relies on tight junctions (e.g., claudin-5, occludin, ZO-1), endothelial cell health, pericytes, and transporters like MFSD2A. Damage from oxidative stress, inflammation, or toxins can be mitigated protectively in models, but true regeneration data (especially post-spike exposure) is limited to preclinical (animal/cell) studies. No human trials confirm reversal for vaccine-related BBB issues.

That said, here’s a synthesis of available data on natural compounds with evidence for protective, strengthening, or reparative effects on BBB integrity. These often act via antioxidant, anti-inflammatory, and signaling pathways (e.g., activating NRF2/WNT/PI3K-AKT while inhibiting NF-?B/MAPK). Focus is on dietary sources or nutraceuticals where animal/in vitro work shows reduced permeability, preserved tight junctions, lower edema, and better endothelial survival.

Key Natural Compounds/Ingredients with Supporting Data
– Curcumin (from turmeric/curry spice): A potent antioxidant and anti-inflammatory. In a 2026 rat model of cervical spinal cord injury (analogous to neurovascular damage), rats on a diet enriched with DHA + curcumin showed preserved walking ability, reduced cell-membrane damage markers, and restored neural repair/communication markers—outcomes similar to healthy controls. Mechanisms include lowering oxidative stress and supporting membrane repair.

– DHA (docosahexaenoic acid, an omega-3 fatty acid):
Supports BBB integrity and transporter expression. A 2026 study showed DHA + curcumin combos enhanced neurological recovery post-injury via membrane repair and reduced inflammation. Broader research links omega-3s (especially DHA) to maintaining BBB structure, reducing permeability in injury/stroke models, and aiding brain delivery.

– Resveratrol (from red grapes, berries, peanuts):
A polyphenol with multiple BBB-protective actions in reviews. It enhances tight junction stability (e.g., ZO-1, claudins), reduces permeability, mitigates oxidative stress/apoptosis in endothelial cells, and improves cerebrovascular function. Systematic reviews link it to better glymphatic clearance and neuroglial health. Common in dietary sources; protective in various disease models.

– Quercetin (from onions, apples, berries, capers):
Flavonoid with BBB-strengthening potential. It modulates signaling (e.g., src-p-gp-MMP-9) to protect tight junctions, reduces permeability, and aids recovery from cerebral ischemia. Often combined with other agents; shows antioxidant and anti-inflammatory effects at the endothelial level.

– NMN (nicotinamide mononucleotide, a NAD+ precursor):
Not a traditional “food” but a natural-derived supplement with striking BBB data. In a 2023 mouse study, NMN (100 mg/kg/day in drinking water) prevented age-related BBB leakage, restored connexin 43 and NAD+ levels in brain endothelium, and reduced stroke-induced brain damage (linked to BBB disruption). It activates protective pathways and counters oxidative stress—relevant for age-related or toxin-driven leakage.

Broader Nutritional Approach (Whole-Foods Focus)
A Mediterranean or antioxidant-rich diet (fruits, vegetables, nuts, seeds, fatty fish) is repeatedly linked in reviews to BBB protection.
Examples include:
– Carotenoids (lutein, beta-carotene, astaxanthin from leafy greens, carrots, tomatoes, berries).
– Anthocyanins (cyanidin, malvidin from berries, red wine, eggplant).
– Polyphenols like catechins (green tea), epicatechin (cocoa), hesperidin (citrus), and fisetin (broccoli).

These often act systemically or via gut-brain axis (a leaky gut can worsen BBB permeability).

Supporting Reviews and Mechanisms
A 2025 open-access review (Kocsis et al., Nutrients) comprehensively covers dozens of plant-derived nutraceuticals (flavonoids, carotenoids, polyphenols, alkaloids, lipids, vitamins). They improve BBB integrity by tightening junctions, boosting efflux transporters (e.g., P-gp), increasing antioxidant defenses, reducing astrocyte swelling/edema, and activating beneficial signaling (WNT, PI3K-AKT, NRF2) while suppressing pro-damage ones (NF-?B, MAPK). Effects seen in vitro (endothelial cell survival) and in vivo (reduced permeability/edema in disease models).

Caveats and practical notes:
– Data is mostly preclinical (mice, rats, cultured cells); human efficacy/safety for BBB repair post-vaccination isn’t established.
– Synergies exist (e.g., DHA + curcumin, or quercetin + resveratrol pairs).
– No strong evidence these reverse spike-induced damage specifically—focus on general protection, reducing ongoing inflammation/oxidative stress.
– Always consult a healthcare provider (especially post-COVID symptoms). Supplements can interact with medications; quality matters (third-party tested).

As well as the above recommendations, here are my two nutritional formulations to help support the body in the healing process:
https://www.healthelicious.com.au/NutriBlast-Anti-Spike.html
https://www.healthelicious.com.au/NutriBlast_DNA_Heart_Mitochondria.html

(Tom: The major point the author does not raise is that I have read people who contracted measles have a lower cancer rate than people who received the vaccine.)

A note to readers: This is a technical document written primarily for a scientific and medical audience. It examines the underlying studies, immunology, epidemiology, and limitations of the available evidence in considerable detail. For readers who do not need that level of detail, this summary contains the central argument and conclusions and may be all that is necessary to read.

Every American now over the age of sixty-nine was almost certainly infected with wild measles as a child. Every American under fifty-eight was born into the era of further-attenuated measles vaccination and has probably never been infected with the wild virus. The boundary between those two populations is currently passing through the seventh decade of life.

The consequence is that measles in the elderly has never been observed in a substantial population whose immunity derives primarily from childhood vaccination, because until now no such elderly population has existed. Before vaccination, the question could not be studied either, since nearly everyone was infected by adolescence. We therefore have almost no direct evidence of what measles susceptibility, disease severity, or mortality will look like when vaccine-derived immunity reaches old age.

There are already reasons to ask what happens as vaccine-derived immunity ages along with the immune systems of the people who carry it. A systematic review and meta-analysis found that, in elimination settings, measles antibody levels decline after vaccination but do not show the same pattern after natural infection. For decades, that decline may have been partly obscured by subclinical boosting when vaccinated people encountered circulating wild virus without developing clinical measles. Elimination largely removed that source of exposure.

Measles itself raises a second question. Infection can erase a substantial portion of the pre-existing antibody repertoire, a phenomenon known as immune amnesia. In the principal study, children lost between 11 and 73 percent of their pre-existing antibody repertoire following infection. That work was conducted in children, whose accumulated immune histories were relatively short and whose capacity to rebuild immune responses was greater than it is in old age. What immune amnesia for other diseases after a measles infection would mean in a seventy- or eighty-year-old with a lifetime of accumulated immunity has not been studied.

There is another major uncertainty. The serological threshold commonly used to define measles protection rests on remarkably limited evidence, beginning with a 1990 study in which only nine people had pre-exposure titers at or below the proposed threshold. A subsequent systematic review found the evidence supporting that threshold to be scant and concluded that it requires further characterization.

There is another major issue. The serological threshold used to define measles immunity is based on nine people studied in 1990, and the field has formally acknowledged that it needs to be recharacterized. None of this predicts a catastrophe. It identifies a gap that becomes measurable around 2033, when the first single-dose cohorts reach sixty-five, and around 2054 for the two-dose cohorts. We do not have to wait that long to begin finding out what happens to vaccine-derived measles immunity as people age. That research is not currently being done.

Public health officials and scientists have assumed that childhood measles vaccination provides protection throughout the human lifespan, even though no fully vaccinated generation has yet reached old age. Once again, an assumption has hardened into an article of faith without the evidence needed to support it.

You can read the full article here:

https://open.substack.com/pub/rwmalonemd/p/measles-immunity-no-twice-vaccinated

In one of Professor Francis Boyle’s final interviews before his death he repeatedly called the mRNA COVID shots “Frankenshots” and described them as biological weapons. He argued the technology involved gain-of-function elements and should be treated under bioweapons law.

He also accused Bill Gates of pursuing a depopulation / eugenics agenda through global health and vaccine programs.

Boyle, the international law professor who drafted the U.S. Biological Weapons Anti-Terrorism Act of 1989, was a sharp critic of the COVID response until the end.

Boyle died on January 30, 2025, at age 74 in Urbana, Illinois. He had remained outspoken about what he saw as medical tyranny and the legal status of the injections.