The Spike Protein, Ferritin and Long COVID: Additional Damage to the Microvasculature

The Spike Protein appears to induce massive release of iron from Ferritin, damaging the microvasculature much like after mini strokes.

I would like to discuss an additional mechanism of microvascular damage today that the Spike Protein may induce. This mechanism can also help to explain the neurological symptoms of Long COVID – and why it resembles post stroke conditions. This mechanism starts with – the Endothelium. Brain endothelial cells contain high amounts of Ferritin.

Iron mediates endothelial cell damage and blood-brain barrier opening in the hippocampus after transient forebrain ischemia in rats
https://pmc.ncbi.nlm.nih.gov/articles/PMC3047193/

SARS-CoV-2 Spike Protein Induces Time-Dependent and Brain-Region-Specific Alterations in Ferroptosis Markers: A Preliminary Study in K18-hACE2 Mice
https://pmc.ncbi.nlm.nih.gov/articles/PMC12897609/

Serum Ferritin Levels Are Associated with Vascular Damage in Patients with Nonalcoholic Fatty Liver Disease.
https://ashpublications.org/blood/article/114/22/5098/77164/Serum-Ferritin-Levels-Are-Associated-with-Vascular

Serum ferritin level during hospitalization is associated with Brain Fog after COVID-19 https://www.nature.com/articles/s41598-023-40011-0

Finish reading: https://open.substack.com/pub/wmcresearch/p/the-spike-protein-ferritin-and-long