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Statin drugs found to accelerate arterial calcification

Newly published research reveals that more frequent statin drug use is associated with accelerated coronary artery and aortic artery calcification, both of which greatly contribute to cardiovascular and all-cause mortality.

Published Aug. 8th, 2012 in the journal Diabetes Care, researchers studied patients with type 2 diabetes and advanced atherosclerosis and found that coronary artery calcification “was significantly higher in more frequent statin users than in less frequent users.” [i]

Furthermore, in a subgroup of participants initially not receiving statins, “progression of both CAC [coronary artery calcification] and AAC [aortic artery calcification] was significantly increased in frequent statin users.”

What is perhaps most alarming about this new finding is that statin drugs have already been shown to significantly increase the risk of developing type 2 diabetes, prompting the FDA on Feb. 27th, 2011, to add “diabetes risk” to the warning label of all statin drugs marketed in this country.

Now, with this latest discovery, it is safe to say, not only do statins likely induce type 2 diabetes in susceptible populations, but they also accelerate the cardiovascular complications associated with the disease — a painfully ironic and highly concerning fact, considering that statins are supposed to reduce cardiovascular morbidity and mortality, not accelerate it.

As we have explored in previous articles, this is probably only the tip of a massive iceberg of statin-associated adverse effects. Our ongoing database project has linked statin drugs to over 300 documented adverse health effects, not the least of which is the ability to weaken the heart muscle, or to increase the risk of type 2 diabetes by 48% in postmenopausal women.

If you know someone on a statin drug, especially someone who also has diabetes or is at risk of developing it, please distribute this information to them, and expose them to the peer-reviewed and published research that already exists on potential naturals alternatives: Health Guide: Statin Drugs.

[i] Aramesh Saremi, Gideon Bahn, Peter D Reaven, Progression of Vascular Calcification Is Increased With Statin Use in the Veterans Affairs Diabetes Trial (VADT). Diabetes Care. 2012 Aug 8. Epub 2012 Aug 8. PMID: 22875226

© August 11th 2012 GreenMedInfo LLC. This work is reproduced and distributed with the permission of GreenMedInfo LLC. Want to learn more from GreenMedInfo? Sign up for the newsletter here www.greenmedinfo.com/greenmed/newsletter.

https://nexusnewsfeed.com/article/health-healing/statin-drugs-found-to-accelerate-arterial-calcification/

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Subtle signs on your hands reveal serious health issues

Hands

Have you ever noticed a sudden change in your hands? Maybe your nails are more brittle than usual, or perhaps you’ve experienced a strange tingling in your fingers. It’s easy to dismiss these changes as minor inconveniences, but sometimes, these subtle signs are early indicators of underlying health issues. Your hands are intricate structures, with a dense network of blood vessels, nerves and skin.

This complexity makes them susceptible to reflecting changes happening elsewhere in your body. By paying close attention to these signals, you gain valuable insights into your overall health. Being aware of these subtle changes allows for earlier diagnosis and treatment, which makes a big difference in preventing more serious health problems down the road.

  • From nail color and texture changes signaling anemia, lung conditions or thyroid problems to skin changes indicating eczema or Raynaud’s phenomenon, your hands offer valuable insights into your overall health
  • Pay close attention to your nails — pale nails suggest anemia, yellowing could indicate lung or liver issues, and changes in texture like pitting or clubbing point to psoriasis or heart conditions
  • Skin changes on your hands, such as persistent dryness, cracking or unusual rashes, might be linked to eczema, thyroid problems or even circulatory issues like Raynaud’s phenomenon
  • Hand pain, swelling and numbness shouldn’t be ignored, as they are symptoms of arthritis (rheumatoid or osteoarthritis), carpal tunnel syndrome, lymphedema or even kidney disease
  • Reduced hand grip strength is increasingly recognized as an indicator of weakened immunity, declining muscle mass with age and underlying heart health, warranting attention to overall well-being

https://nexusnewsfeed.com/article/home-family-pets/subtle-signs-on-your-hands-reveal-serious-health-issues/

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“Seek them out and destroy them where they live.”

Remembering Merck’s Australian doctor hit list.

John Leake writes:

This evening I pondered that news of Caroline Kennedy’s hit letter against her cousin, RFK, Jr., and the fact that she was the Biden Administration’s Ambassador to Australia, and fact that she has served as a powerful ambassador for Merck’s Gardasil vaccine.

The association of Australia and Merck reminded me of the company’s “seek out and destroy” campaign against Australian doctors who expressed concern that the company’s blockbuster Vioxx seemed to be causing heart attacks and strokes. As was reported by CBS in May 2009:

Merck made a “hit list” of doctors who criticized Vioxx, according to testimony in a Vioxx class action case in Australia. The list, emailed between Merck employees, contained doctors’ names with the labels “neutralise,” “neutralised” or “discredit” next to them.

According to The Australian, Merck emails from 1999 showed company execs complaining about doctors who disliked using Vioxx. One email said:

“We may need to seek them out and destroy them where they live …”

During this same period in the United States, Merck was accused of concealing negative results of clinical Vioxx trials from the FDA and paying reputable doctors to put their names on research they did not conduct or write up. The company also published a fake journal, paying Elsevier to create a phony publication to serve as a marketing tool titled the Australasian Journal of Bone and Joint Medicine.

Ultimately the company was found guilty of knowingly concealing data about the elevated risk of stroke and heart attack from Vioxx and agreed to pay a class action settlement to stroke and heart attack victims totaling $4.85 billion.

I wonder if the nice folks at Merck would ever yield to the temptation to overstate the benefits of the HPV vaccine and downplay its risks, as some plaintiffs have alleged. I also wonder if the company’s PR department might yield to the temptation to smear RFK, Jr. during his Senate confirmation process.

Or am I just being cynical?

https://petermcculloughmd.substack.com/p/seek-them-out-and-destroy-them-where

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BREAKTHROUGH: The Endothelial Phase of Spike Protein Amyloid Deposition Disease (SPED) is Just the Beginning: The Dangers of Reinfection

Kaempferol Sources

  • Environmental allergies affect 20% of Americans, causing a total of 4 million lost workdays and $8 billion in annual economic losses. Kaempferol, found in leafy greens, shows promise in natural allergy relief
  • The intestinal enzyme RALDH2, boosted by kaempferol, converts vitamin A-derived retinal to retinoic acid, which helps suppress allergic immune responses through regulatory T-cell development
  • Following an elimination diet will help identify food allergies, but complete avoidance isn’t recommended as it leads to malnutrition
  • Vitamin C (300 to 500 milligrams daily) demonstrates antihistamine properties, reducing plasma histamine levels by 40% over two weeks, with red peppers, citrus fruits and parsley being excellent natural sources
  • Quercetin, particularly abundant in onion skins, apples and berries, shows significant antiallergy activity by modulating histamine release, with recommended doses of 500 to 1,000 milligrams taken twice to four times daily

…”The rapid decrease in body temperature and allergic diarrhea observed after… …administration were significantly suppressed in mice that were administered kaempferol.”

Kaempferol is abundant in leafy green veggies, such as broccoli, spinach and cabbage. According to a study published in Molecules, broccoli happens to have the highest concentration, while blueberries and onions are also good choices…

…

In the video above,19 Dr. Jin Sung explains the role of quercetin in helping relieve seasonal allergies. According to his findings, he believes that quercetin possesses the greatest antiallergy activity compared to other flavonoids. Specifically, it works by modulating the release of histamine from basophils and mast cells. This process was also documented in a study published in Biomedicine & Pharmacotherapy.

When it comes to dosing, Sung recommends taking 500 to 1,000 mg of quercetin, two to four times a day during allergy season to help manage the symptoms. Begin with the lowest dose first — 500 mg, twice a day — and gradually increase if necessary. The reason for this is because the half-life of quercetin is 3.5 to 7.5 hours, so it’s best taken in divided doses.

To help improve the results, I recommend taking other supplements to create synergistic effects. These include stinging nettle, butterbur extract, mangosteen extract, ginger, vitamin C and vitamin D.

Like vitamin C and kaempferol, quercetin is also found in many whole foods. These include citrus fruits, green leafy vegetables, broccoli, apples, onions, green tea, red grapes, dark cherries and berries, such as blueberries and cranberries. From these examples, the highest amounts are found in apples — especially the skins — as well as onions, broccoli, cherries, berries and green tea.

https://nexusnewsfeed.com/article/health-healing/kaempferol-a-potent-antiallergic-flavonoid/