Capsaicin: Inhibiting Spike Protein-Induced Line-1 Retrotransposition

Retrotransposition: a transposable element that undergoes transposition from one place to another in the genome of a cell by forming an intermediate RNA transcript from which a copy of the DNA of the transposable element is made using a reverse transcriptase and inserted into the genome at a new location.

In other words having your own DNA overwritten by elements of the spike protein. Not good.

What this article describes is research showing capsaicin (from the capsicum family – peppers and chili) inhibits the spike protein harm. You will be pleased to know chili and capsaicin are two of the 64 ingredients in my new batch of Anti-Spike Blend. https://www.healthelicious.com.au/NutriBlast-Anti-Spike.html

Or, as the good doctor writes:

Now that we know the Spike Protein is able to hijack Line-1 and retrotranscribe its RNA into our DNA, it is imperative to seek remedies for this phenomenon. Please see my most recent post for details about the Spike and Line-1. In that post I promised to search for natural solutions. Again, Nature does not fail to deliver. In the humble yet pungent chili pepper we find a powerful ally. Capsaicin. This nutraceutical is able to inhibit Line-1 retrotransposition, making it a potentially magnificent therapeutic.

Though I am quite certain that all reading this know what Capsaicin is, here is offered a brief primer:

Capsaicin was first isolated in 1816 by Christian Bucholz. Capsaicin is a chili pepper extract, genus Capsicum, with analgesic properties. Its chemical composition was first determined in 1919. They explained the biosynthetic pathway in the 1960s. Since its discovery, it is used as a homeopathic remedy to treat burning pain using the concept of ”treating like with like” or counter-irritant. The first reports of its pain-relieving properties appeared in the mid-1850s as a recommendation to use it for parts of the body that burn or itch. Since the first reports, one uses various preparations of capsaicin to treat a variety of chronic painful conditions. Systematic reviews have shown that capsaicin is efficacious in treating a variety of conditions, including:

Nondiabetic neuropathic pain

Postherpetic neuralgia

Osteoarthritis

Chronic musculoskeletal pain

Post-mastectomy pain syndrome

Burning mouth syndrome

Overactive bladder

Gastropathy

Postoperative nausea and vomiting

Pruritus

Pruritus ani

Postoperative sore throat

Improving cough reflex sensitivity in patients with a history of dysphagia and other swallowing related disorders

Chemotherapy- and radiotherapy-induced mucositis.

Capsaicin
https://www.ncbi.nlm.nih.gov/books/NBK459168/#

To the above mentioned abilities, we can add several more – especially with regards to the Spike Protein. Let’s first start with Capsaicin’s ability to inhibit Line-1.

In this study, we found a novel activity of capsaicin, the inhibition of L1 retrotransposition. Since L1 retrotransposition is proposed to be mutagenic and can cause tumorigenesis [9,10], capsaicin may suppress the progression of tumorigenesis through the inhibition of L1-mediated mutagenesis. Collectively, capsaicin possesses several properties that exhibit anti-cancer activities and can therefore be a potent candidate for use in anti-cancer therapies, especially in the case of certain cancers where L1 plays a role in tumorigenesis [9,10].

In conclusion, we demonstrated the potential of capsaicin for inhibiting retroviral RT activity and suppressing L1 retrotransposition, possibly via inhibition of RT activity of ORF2p. Our findings suggest the potential of capsaicin for suppressing cancer development and they may facilitate the studies of capsaicin or related compounds, capsaicinoids, for cancer prevention and treatment.

https://wmcresearch.substack.com/p/friday-hope-capsaicin-inhibiting