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“Children using anti-epileptic medication have reduced plasma levels of vitamin E, a sign of vitamin E deficiency. So, doctors at the University of Toronto gave epileptic children 400 IU of vitamin E per day for several months, along with their medication. This combined treatment reduced the frequency of seizures in most of the children by over 60 percent. Half of them “had a 90 to 100 percent reduction in seizures”. This extraordinary result is also proof of the safety of 400 IU of vitamin E per day in children (equivalent to at least 800 to 1,200 IU/day for an adult). “There were no adverse side-effects,” said the researchers. It also provides a clear example of pharmaceutical use creating a vitamin deficiency, and an unassailable justification for supplementation.” Ogunmekan AO, Hwang PA “A randomized, double-blind, placebo-controlled, clinical trial of D-alpha-tocopheryl acetate (vitamin E), as add-on therapy, for epilepsy in children”, Epilepsia, 1989 Jan-Feb; 30(1):84-9