Supplementation with Riboflavin (Vitamin B2) for Migraine Prophylaxis in Adults and Children: A Review

Eleven eligible articles were found: seven involved studies with adults and four involved studies with children. The results indicated that supplementation with vitamin B2 in adults can play a positive role in reducing the frequency and duration of migraine attacks with no serious side effects.

https://pubmed.ncbi.nlm.nih.gov/26780280/