Surprising side effects of Acetaminophen (Tylenol/Panadol)

Written By: Kelly Brogan, M.D.

You know Tylenol can relieve a headache, but are you aware it can cause other side effects, such as increased risk of death or heart toxicity?

Tylenol: Helping or Hurting?

Have you ever popped a Tylenol to push through that annoying headache and get on with your day? Most of us have. Each week, millions of Americans take one of the 600 medicines that contain acetaminophen, Tylenol’s active ingredient, for various aches and pains. Acetaminophen is the most common drug ingredient in the US, but this ‘harmless drug’ is linked to over 110,000 injuries and deaths per year.

How can Tylenol, which is doled out like candy, be bad for you? Amazingly, no one really knows how acetaminophen works [1], but people do know that this drug gets to your brain. Tylenol in your brain is concerning because it depletes glutathione [2], an antioxidant that is especially necessary for brain health. Our bodies depend on antioxidants to balance oxidative damage and inflammation. If you’re popping a Tylenol with your morning antioxidant-rich KB Smoothie, Tylenol may rob you of the smoothie’s benefits!

Beyond Liver Damage

Most people have heard that Tylenol can damage the liver (has anyone ever drunkenly warned you to take a Motrin, not a Tylenol, to prevent a hangover?). But since everything in our bodies is connected, it’s not surprising that Tylenol can do damage beyond your liver. A recent study showed that people who took Tylenol had increased risks of death, heart toxicity, gastrointestinal bleeding, and kidney damage [3]. Importantly, people who took more Tylenol suffered more damage.

It’s also scary how Tylenol affects mood. After swallowing 1000 mg of Tylenol, people exhibited less empathy and blunted positive emotions. For reference, 1000 mg is two extra-strength Tylenol tablets, and the ‘safe’ range is 3000 mg per day. This means that popping two Tylenols can affect you physically and emotionally!

If you’re pregnant or looking to become pregnant, please be especially careful about taking Tylenol. Research has shown that children exposed to acetaminophen in the womb had behavioral, communication, and motor skill problems. Another study linked prenatal acetaminophen exposure with increased ADHD-like behaviors and medication use.

What about other painkillers?

Hopefully you’re convinced to think twice before taking a Tylenol, but what about other pain-relievers like Motrin, Aleve, or Advil? These non-steroidal anti-inflammatory drugs (NSAIDs) must be safe, since thirty million people take them every day! Not so fast…

Women who recognize the importance of hormonal balance should be wary. NSAIDs can mess with ovulation, especially progesterone levels, after only 10 days of use [4]. Additionally, NSAIDs injure the small intestine; in one study, 71% of NSAID users showed small intestinal damage, compared to 10% of non-users [5]. Damaged intestines can lead to intestinal permeability, or “leaky gut.” Leaky gut has been linked to depression, ADHD, and allergies. NSAIDs can cause leaky gut [6] and harm your microbiome, the trillions of beneficial bacteria that live in and on us. Disrupting our bacteria can do more damage than we realize!

How can I relieve my headache?!

Now that you know the surprising dangers of Tylenol and other NSAIDs, what should you take for headaches and other aches and pains? Turmeric, the yellow root found in curry powder, contains a powerful anti-inflammatory and pain reliever called curcumin. This has been used in Ayurvedic and Chinese medicine as a treatment for pain, digestive disorders, and wound healing for centuries. Many studies show the beneficial effects of curcumin; curcumin works as well as ibuprofen to alleviate pain from knee osteoarthritis [7] and PMS [8]. Next time you have a headache, try 1-2 grams of curcumin – or a turmeric latte!

© March 5th 2017 GreenMedInfo LLC. This work is reproduced and distributed with the permission of GreenMedInfo LLC. Want to learn more from GreenMedInfo? Sign up for the newsletter here: http://www.greenmedinfo.com/greenmed/newsletter

Interval Walking Training — Going Beyond Step Count

  • Interval Walking Training (IWT) was observed to help improve lower blood pressure, depression symptoms and stroke risk while enhancing muscle strength and immune system function
  • Moderate-intensity exercise like walking is highly beneficial, with benefits increasing from 2,000 to 12,000 steps daily without apparent upper limits on positive effects
  • Japanese researchers have developed innovative walking techniques, including IWT and slow running, offering accessible solutions for people of all ages and fitness levels
  • Slow running and light-intensity exercise activates brain genes, increases neural activity in the hippocampus and provides mental health benefits without requiring athlete-like levels of discipline
  • Walking is enhanced through various methods like weighted vests, Nordic walking, outdoor nature walks, social walking and using the time for creative thinking and personal development

https://articles.mercola.com/sites/articles/archive/2025/01/11/interval-walking-training.aspx

‘Wide Body of Science’ Links Endocrine-disrupting Chemicals to Infertility in Women

Endocrine Chemicals Infertility

In a Frontiers in Public Health review article, researchers report on the wide body of science connecting adverse effects to the female reproductive system, such as infertility, with exposure to endocrine-disrupting chemicals, or EDCs.

The authors call these effects a significant concern for public health, as there has been growing evidence of EDCs with risk factors for decreased fertility.

Infertility “affects a substantial proportion of the world’s population with approximately one in six people affected,” the researchers note.

They continue:

“Over the last 70 years, global fertility has been constantly in decline due to behavioral and societal changes … emerging evidence has shown that infertility incidence is linked to exposure to environmental factors such as tobacco, alcohol, and a wide range of endocrine-disrupting chemicals (EDCs) including pesticides (chlorpyrifosglyphosate, dichlorodiphenyltrichloroethane [DDT] and methoxychlor), phthalatespolychlorinated biphenyls (PCB), dioxins, and bisphenols.”

In this review, over 100 studies are summarized to showcase the link between EDC exposure and reproductive effects in women, including infertility and related diseases such as endometriosis, premature ovarian insufficiency, or POI, and endocrine axis dysregulation.

https://childrenshealthdefense.org/defender/endocrine-disrupting-chemicals-infertility-women/

Attitude Is Everything

A famous writer was in his study.  He picked up his pen and began writing:
“Last year, my gallbladder was removed.
I was stuck in bed due to this surgery for a long time.
The same year I reached the age of 60 and had to give up my favorite job.
I had spent 30 years of my life with this publishing company.
The same year I experienced the death of my father.
In the same year my son failed in his medical exam because he had a car accident. He had to stay in the hospital with a cast on his leg for several days.
And, the destruction of the car was a second loss.
Alas! It was such a bad year!”

When the writer’s wife entered the room, she found her husband looking dejected, sad and lost in his thoughts.  
She carefully and surreptitiously read what he had written, and silently left the room and came back shortly with another piece of paper on which she had written her summary of the year’s events and placed it beside 
her husband’s paper.  
 
When her husband saw that she had written something in response to his account of the year’s events, he read:

“Last year I finally got rid of my gallbladder which had given me many years of pain.  
I turned 60 with sound health and retired from my job. 
Now I can utilize my time to write better and with more focus and peace.
The same year my father, at the age of 95 without depending on anyone and without any critical conditions, met his Creator.
The same year, God blessed my son with life.
“My car was destroyed, but my son was alive and without permanent disability.
This year was an immense blessing and it passed well!”

~ MORAL ~
In our daily lives we must see that it’s not happiness that makes us grateful, but gratefulness that makes us happy. There is always, always something to be thankful for.
 
ATTITUDE IS EVERYTHING
Attitude is the one thing that we always, in every circumstance, have control over.