A small new study by Emory University scientists suggests that people with mild cognitive impairment and disturbed sleep — two hallmarks of early dementia — who take high daily doses of vitamin D may perform better on a standard cognitive test.
COVID mRNA Vaccine Hides Up to 30% of Endotoxin Activity in FDA Test
Studies show lipid particles can take up endotoxin and hide over 90% of it from testing, raising questions about whether mRNA vaccine lipids conceal manufacturing E. coli LPS endotoxin contamination.
Studies show lipid particles can take up endotoxin and hide over 90% of it from testing, raising questions about whether mRNA vaccine lipids conceal manufacturing E. coli LPS endotoxin contamination.
All FDA-approved and emergency-use-authorized mRNA vaccines use E. coli to produce so-called starting DNA or other manufacturing materials, creating a lipopolysaccharide (LPS) endotoxin contamination risk that manufacturers test for in the finished shots.
Endotoxin has been shown to drive cardiac injury and abnormal clotting in experimental studies, and other outcomes that overlap with myocarditis, blood clots, and other serious events reported after Pfizer’s COVID-19 mRNA vaccine, raising the question of whether endotoxin was adequately excluded as a contributor.
No publicly available information tells us specifically how much endotoxin is present in finished mRNA vaccine vials.
In a January 2022 memo, the FDA reported adding a known amount of endotoxin to three samples of Moderna’s finished COVID vaccine to check whether its test could detect it.
Its test only recovered 80%, 71%, and 70% of the added activity.
Meaning 20%, 29%, and 30% of the control signal went undetected while the added endotoxin was present in the samples.
The endotoxin was still there.
FDA knew how much it had added.
Yet something in the vaccine samples prevented the test from detecting up to 30% of its activity.
FDA nevertheless accepted all three results, raising questions:
If the test missed up to 30% of a control added after manufacture, what could it miss when endotoxin enters the vaccine’s lipid particles during manufacture?
Why did FDA call the measured loss only “slight inhibition”?
And why did the agency allow a complete finished-product release test to wait until after its Spikevax approval decision?
Why have regulators and manufacturers not told us exactly how much LPS endotoxin is present in finished mRNA vaccine vials?
Why do post-mRNA vaccination adverse events track endotoxin exposure symptoms?
Australian regulator TGA did test Pfizer’s mRNA COVID vaccine batches as “less than 5 EU/mL.”
But that means the assay couldn’t see endotoxin above a prespecified cutoff, and only after it was diluted.
It is not a count of how much total endotoxin is in each vial.
Moreover, studies examined below found that liposomes and other lipid preparations can hide over 90% of incorporated endotoxin from detection, raising the question of what happens in the lipid nanoparticles used in mRNA vaccines.
FDA’s January 4, 2022 memo identifies the three finished Spikevax lots it tested for bacterial endotoxin; the recovery figures and redacted results appear on the following page.
FDA’s Spikevax results table shows only 80%, 71%, and 70% recovery of added endotoxin activity at 1:1,000 dilution. FDA and Moderna’s actual lot results, and the passing specification, are redacted, while every lot is marked “yes.” (Note: “Spike recovery” here has nothing to do with the vaccine’s purported spike protein. A spike is a known amount of endotoxin deliberately added to a sample to check how much the test can detect.)
https://jonfleetwood.substack.com/p/covid-mrna-vaccine-hides-up-to-30
Louis Kuhne Said
He might have omitted meat in his dietary recommendations but the rest of it sounds majorly accurate.
Quote of the Day
“The best government is that which teaches us to govern ourselves.”
Johann Wolfgang von Goethe – Writer (1749-1832)
(Tom: In case you had not looked lately, we do not have the best government!)
How to Actually Get Microplastics Out of Your Body
Microplastics are building up inside your brain, blood, and reproductive tissue, and most detox protocols do nothing to remove them. This episode gives you the cellular science behind why toxins accumulate, which three detox pathways control your ability to excrete them, and what the latest research shows actually moves microplastics, heavy metals, BPA, and benzene out of your body.
Host Dave Asprey sits down with Dr. John Gildea, a Johns Hopkins-trained PhD with 60 scientific publications and over 20 NIH-funded studies, and David Roberts, co-founder of Mara Labs and co-creator of BrocElite, the only naturally derived stable form of sulforaphane available in a capsule. Together they bring decades of research-backed biohacking and functional medicine insight into one of the most pressing longevity conversations of our time.
They break down the lysosome, your cell’s built-in incinerator, and explain exactly why it gets clogged with microplastics, advanced glycation end products, and other toxins that won’t break down. New research shows that sulforaphane triggers a process called lysosomal surface translocation, which releases those trapped particles so your body can finally excrete them. An in-house Mara Labs study confirmed the excretion pathway: microplastics come out in feces. In the original study, the individual measured the highest microplastic levels ever recorded, and a repeat study a year later showed dramatically lower baseline microplastic levels, suggesting consistent use compounds the benefit over time.
You’ll Learn:
-Why microplastics accumulate inside lysosomes and what sulforaphane does to release them
-How the three detox pathways, glutathione, glucuronidation, and sulfation, work together to remove every major class of toxin
-What an in-house study revealed about how and where microplastics actually leave the body
-How toxic estrogen metabolites form and why sulforaphane is the most effective natural tool to reroute them
-Why berberine supports sleep optimization, ketosis, and blocks a cancer growth pathway most drugs cannot touch
-How sulforaphane boosts BDNF and neuroplasticity at the cellular level
-What microplastic sources in your home, including your dryer, rugs, and receipts, are doing to your toxin load daily
-Why losing weight releases stored toxins and what to take to protect your brain and metabolism during fat loss
-How sulforaphane activates the same AMPK longevity pathways triggered by fasting without restricting food
Click to view the video: https://www.youtube.com/watch?v=o3-ngPrYbvk
5 Supplements Your Parents Should Be Taking (But Likely Aren’t)
In this video, Rhonda Patrick discusses the supplement regimen she has her mom & dad following. Topics covered include:
• Can a simple multivitamin actually reverse brain aging?
• Why supplementing vitamin D is a no-brainer for older adults
• Should older adults supplement with omega-3?
• Why Rhonda’s dad supplements with ubiquinol
• What happened when Rhonda’s mom started taking sulforaphane
Click to view the video: https://www.youtube.com/watch?v=AaXbq97Obyg
The 72-Hour Rule for Building Muscle | Dr. Andy Galpin
Dr. Andy Galpin explains the fundamentals of training for muscle growth, focusing on mechanical tension as the primary driver, the “72-hour rule” for stimulating each muscle, why rep ranges from 5 to 30 can produce equal hypertrophy as long as sets are taken within 1 to 3 reps of failure, and how structured progressive overload is the most common missing piece when progress stalls.
Click to view the video: https://www.youtube.com/watch?v=4Xg0osmXufU
Scientists Won a Nobel Prize for This — 20 Foods That Switch On Your Anti Aging Cells
Spermerdine is in wheat germ, popcorn, pears, green peas, lentils, cauliflower, broccoli, mushrooms, red kidney beans, cooked chicken, whole grain bread, nuts, oranges, mango, natto, aged cheese, liver. durian, amaranth, soybeans.
Click to view the video: https://www.youtube.com/watch?v=chdyq9HrCK4
10 Cortisol Killing Drinks That Increase Blood Flow
Feeling constantly wired, tired, or stressed? These 10 cortisol-calming drinks are backed by real clinical research on stress hormones and circulation — not hype. Discover how chamomile, hibiscus, beetroot juice, and an ancient Ayurvedic tonic called “moon milk” may help your body manage stress more efficiently while supporting healthy blood flow. Drink #4 takes 30 seconds and uses something already in your kitchen. Drink #10’s name literally translates to “the smell of a horse.” Backed by published studies, explained simply, and easy to start today. Watch now to find out which drink deserves a permanent spot in your routine.
Sauerkraut After 60: What It Really Does to Your Gut
All Sauerkrauts are not the same…
Click to view the video: https://www.youtube.com/watch?v=-WjL_YP308E