I believe we now have a cornerstone piece of the puzzle as to why SARS-CoV-2 and its Spike Protein induce such a wide array of pathologies. The Spike Protein causes massive Endoplasmic Reticulum (ER) stress and, depending upon the individual, this can manifest in a wide range of diseases.
What astounds me is that this was known in 2007.
Expression of the viral spike protein significantly induced ER stress and Cxcl2 mRNA upregulation, while expression of the other structural genes did not.
The coronavirus spike protein induces endoplasmic reticulum stress and upregulation of intracellular chemokine mRNA concentrations
https://pubmed.ncbi.nlm.nih.gov/17670839/
Please understand the finding. EXPRESSION of Spike Protein. This means that if your cells EXPRESS the Spike Protein, it causes ER stress. I leave it to the reader to do the math.
ER stress can induce Diabetes, Neurodegeneration, Cancer and PRION FORMATION.
Endoplasmic Reticulum Stress in Disease Pathogenesis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653419/
ER stress causes widespread protein aggregation and prion formation
https://rupress.org/jcb/article/216/8/2295/39185/ER-stress-causes-widespread-protein-aggregation
I will continue to work on the implications of this finding.
The cat is really out of the bag now…
https://wmcresearch.substack.com/p/massive-discovery-known-in-2007-expressing