Can a Spice Rival a Drug? 10 Head-to-Head Trials Put It to the Test

Spice vs Drug 10 Trials

Ten head-to-head clinical trials — pulled from the GreenMedInfo archive — in which honey, turmeric, saffron, ginger and a handful of other kitchen staples matched or outperformed prescription medications. Each one links to the full research write-up.

For nearly two decades, GreenMedInfo has done one thing most health publishers never bother with: we go into the National Library of Medicine and pull out the studies where researchers put a natural substance directly against a drug — same condition, same patients, same scoring — and then publish what they found.

Those studies exist. There are thousands of them. They just don’t get press releases, because nobody holds a patent on honey.

Below are ten of the most striking. Every one is a human trial. Every one is indexed in our database. And every one links to the long-form article where you can read the methodology, the numbers and the citations for yourself.

A word before we start: this is research information, not medical advice. Several of these trials are small. Some are single studies that have not been replicated. I have flagged which ones have the strongest designs. Read them, bring them to your practitioner, and decide for yourself. That is the entire point of having the archive.

Finish reading: https://open.substack.com/pub/sayerji/p/they-compared-the-spice-to-the-drug

Quote of the Day

“It’s no use going back to yesterday, because I was a different person then.” – Lewis Carroll, Alice in Wonderland

Poop, Peppers and a Mouse in the Brine

Cyclospora Venn Diagram

The Great Mystery of the Mexican Lettuce

FDA has finally discovered Cyclospora at the Mexican operations linked to this summer’s record-breaking outbreak: one positive sample came from a tank holding outgoing wastewater at the Taylor Farms de Mexico processing plant, and another from a drainage ditch at one of its lettuce growers.

Nearly 13,000 Americans got sick. More than 570 were hospitalized. Two died.

And yet FDA says there is still “not enough evidence to conclusively determine how contamination occurred.”

Really?

Cyclospora is a fecal-oral parasite. Humans are its known host. It gets onto food when human feces contaminate water or soil.

So somewhere between human feces, wastewater, a drainage ditch next to a lettuce field, and Cyclospora showing up in all, lies one of the great unsolved mysteries of modern food safety. The FDA still can’t quite figure out the relationship.

So we made the Venn diagram for them.

Keep reading: https://open.substack.com/pub/rwmalonemd/p/poop-peppers-and-a-mouse-in-the-brine

Silencing the Alarm: Why GLP-1 Drugs Are the Most Expensive Way Ever Devised to Ignore the Root Cause of Metabolic Disease

GLP-1 and Smoke Alarm

A lifelong prescription for a problem no one is trying to solve: a root-cause and risk-benefit reckoning

magine your smoke alarm goes off in the middle of the night. You have two choices. You can find the fire. Or you can buy a subscription service that injects a chemical into the alarm once a week so it stops making noise, while the house keeps burning.

For a growing share of the population, the second option is now the standard of care.

Around 12% of U.S. adults are now taking a GLP-1 drug like Ozempic, Wegovy, Mounjaro, or Zepbound (Associated Press, citing KFF). In 2025 alone, Eli Lilly’s tirzepatide franchise brought in about $36.5 billion, outselling Keytruda, the cancer drug long considered the most lucrative product in pharmaceutical history (BioSpace). The leading medical societies now say these drugs, once started, are meant for “long-term or lifelong use” (Obesity, 2026).

Read that again. Lifelong. For a condition that barely existed at population scale two generations ago.

That is the absurdity I want to examine. My argument is not that these drugs do nothing; they clearly change the numbers on the scale and on the lab report. My argument is that they do nothing to address why those numbers went wrong in the first place. And once you see the full ledger of risks against that backdrop, the approach looks less like a medical breakthrough and more like an elaborate, profitable way of not asking the obvious question.

https://sayerji.substack.com/p/silencing-the-alarm-why-glp-1-drugs

 

Quote of the Day

“Courage and perseverance have a magical talisman, before which difficulties disappear and obstacles vanish into air.” – John Quincy Adams, 6th President of the United States (from 1825 to 1829)

The Great Cholesterol Lie and The Dangers of Statins

•There is a widespread belief that elevated cholesterol is the “cause” of cardiovascular disease. However, a large body of evidence shows that there is no association between the two and the real data shows lower cholesterol significantly increases one’s risk of death.

•An alternative model (which the medical industry buried) proposes that the blood clots the body uses to heal arterial damage, once healed, create the characteristic atherosclerotic lesions associated with heart disease.

•The evidence for the blood clot model is much stronger than the cholesterol hypothesis and provides many critical insights for treating heart disease.

•The primary approach to treating heart disease is to prescribe cholesterol lowering statin drugs (to the point, nearly a trillion dollars have now been spent on them).

•Unfortunately, the benefits of these highly toxic drugs are minuscule (e.g., at best taking them for years extends your life by a few days) and the harms are vast (statins are one of the most common pharmaceuticals that severely injure patients).

•Multiple 2026 studies have further shown statins do not extend the lives of the healthy individuals they are primarily prescribed to, while a new wave of expensive patented cholesterol drugs is being approved simply for lowering cholesterol—many of which are being marketed to the same “statin intolerant” patients the industry insists are imagining their injuries.

•In this article we will explore the specific injuries caused by statin drugs, the forgotten causes of cardiovascular disease, and our preferred treatments for heart and vascular diseases.

Best Protein For…

Today, I want to share the specific type of protein you should focus on for your specific health concern:

1. Aging
The best types of protein are:
• Eggs
• Oysters or shellfish once a week
• Red meat once or twice a week
• Beef liver once a week
• Fatty fish twice a week
• Chicken and turkey (if you don’t do well with excess iron)

2. Osteoporosis or osteopenia
The best type of protein is:
• Salmon

3. Anemia
The best types of protein are:
• Oysters
• Beef liver twice a week
• Red meat

4. Digestive problems
The best types of protein are:
• Hamburger
• Eggs
• Beef liver once per week

5. Macular degeneration
The best types of protein are:
• Eggs
• Oysters
• Seafood

4. Inflammation
The best type of protein is:
• Fatty fish

5. High blood pressure
The best type of protein is:
• Salmon

6. Depression
The best type of protein is:
• Salmon

7. Anxiety
The best type of protein is:
• Beef liver

8. Muscle building
The best type of protein is:
• Red meat

9. Gallstones
The best types of protein are:
• Scallops
• Mussels
• Clams

10. Detoxification
The best types of protein are:
• Beef liver
• Red meat

11. Fatty liver
The best type of protein is:
• Eggs
12. Diabetes

The best types of protein are:
• Fatty fish
• Beef

Dr. Eric Berg, DC, not MD; information only