{"id":67675,"date":"2026-10-18T16:51:23","date_gmt":"2026-10-18T05:51:23","guid":{"rendered":"https:\/\/www.tomgrimshaw.com\/tomsblog\/?p=67675"},"modified":"2026-10-18T16:51:23","modified_gmt":"2026-10-18T05:51:23","slug":"vitamin-c-plus-dmso","status":"publish","type":"post","link":"https:\/\/www.tomgrimshaw.com\/tomsblog\/?p=67675","title":{"rendered":"Vitamin C plus DMSO"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-67676\" src=\"https:\/\/www.tomgrimshaw.com\/tomsblog\/wp-content\/uploads\/2026\/10\/Vitamin_C_plus_DMSO.jpg\" alt=\"Vitamin C plus DMSO\" width=\"548\" height=\"680\" srcset=\"https:\/\/www.tomgrimshaw.com\/tomsblog\/wp-content\/uploads\/2026\/10\/Vitamin_C_plus_DMSO.jpg 548w, https:\/\/www.tomgrimshaw.com\/tomsblog\/wp-content\/uploads\/2026\/10\/Vitamin_C_plus_DMSO-242x300.jpg 242w\" sizes=\"auto, (max-width: 548px) 100vw, 548px\" \/><\/p>\n<p>A 30 percent vitamin C solution dissolved in DMSO cleared 86 percent of basal cell skin cancer lesions within eight weeks in a clinical trial. In a randomized study published in Biomedicine &amp; Pharmacotherapy, researchers tested a topical mix of high-concentration ascorbic acid and dimethyl sulfoxide, a solvent that helps substances penetrate deeply into the skin.<\/p>\n<p>Applied twice daily for eight weeks, the combination produced complete clearance in 13 of 15 lesions (86.7 percent) among patients with low-risk basal cell carcinoma. This rate exceeded that of the standard topical treatment imiquimod, which cleared 8 of 14 lesions (57.1 percent). The vitamin C\u2013DMSO formulation also caused fewer side effects and avoided the lasting skin hypopigmentation sometimes seen with conventional topical therapies.<\/p>\n<p>Because basal cell carcinoma is the most common form of skin cancer worldwide, these early results suggest a possible low-cost, non-invasive option. Larger trials are still required before the approach can be adopted as standard care.<\/p>\n<p>[Burke, B., &amp; Bailie, J.-E. (2022). Randomized trial of topical ascorbic acid in DMSO versus imiquimod for the treatment of basal cell carcinoma. Biomedicine &amp; Pharmacotherapy, 148, 112710. DOI: 10.1016\/j.biopha.2022.112710]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A 30 percent vitamin C solution dissolved in DMSO cleared 86 percent of basal cell skin cancer lesions within eight weeks in a clinical trial. In a randomized study published in Biomedicine &amp; Pharmacotherapy, researchers tested a topical mix of high-concentration ascorbic acid and dimethyl sulfoxide, a solvent that helps substances penetrate deeply into the &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.tomgrimshaw.com\/tomsblog\/?p=67675\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Vitamin C plus DMSO&#8221;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5,6],"tags":[],"class_list":["post-67675","post","type-post","status-publish","format-standard","hentry","category-general-interest","category-health-tips"],"_links":{"self":[{"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=\/wp\/v2\/posts\/67675","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=67675"}],"version-history":[{"count":1,"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=\/wp\/v2\/posts\/67675\/revisions"}],"predecessor-version":[{"id":67677,"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=\/wp\/v2\/posts\/67675\/revisions\/67677"}],"wp:attachment":[{"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=67675"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=67675"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=67675"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}