![\"Luteolin\"](\"https:\/\/www.tomgrimshaw.com\/tomsblog\/wp-content\/uploads\/2026\/07\/Luteolin.jpg\")
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In a open-label pilot study published in *Clinical Therapeutics*, researchers investigated the effects of a dietary supplement containing the anti-inflammatory flavonoid luteolin in children with autism spectrum disorder (ASD). The 26-week study included children diagnosed with ASD who received a formulation containing luteolin (a flavonoid found in celery and chamomile), along with quercetin and rutin, designed to enhance absorption and provide antioxidant and anti-inflammatory effects. Because the study was open-label, all participants received the supplement and there was no placebo control group.<\/p>\n
Behavioral changes were measured using standardized tools, including the Aberrant Behavior Checklist (ABC) and the Vineland Adaptive Behavior Scales (VABS). After 26 weeks, researchers reported reductions of approximately 26% to 35% in ABC subscales, including lethargy (social withdrawal), stereotypy (repetitive behaviors), hyperactivity, and inappropriate speech. Improvements were also observed in adaptive functioning domains such as communication and daily living skills. However, as a small pilot study without a control group, the findings are considered preliminary and require confirmation in larger randomized controlled trials.<\/p>\n
PMID: 23688534<\/p>\n","protected":false},"excerpt":{"rendered":"
In a open-label pilot study published in *Clinical Therapeutics*, researchers investigated the effects of a dietary supplement containing the anti-inflammatory flavonoid luteolin in children with autism spectrum disorder (ASD). The 26-week study included children diagnosed with ASD who received a formulation containing luteolin (a flavonoid found in celery and chamomile), along with quercetin and rutin, … <\/p>\n