Please read John Leake’s insightful post about Pfizer’s checkered past and how The Pfizer Papers offers further evidence of the company’s decades-long anti-human, profits-first approach to drug development and sales.<\/p>\n
When I was born, my maternal great grandmother gave me a generous gift of Pfizer stock. She had been impressed by Pfizer\u2019s key role in discovering how to mass produce penicillin during World War II (in which her son was killed in action). Eighteen years later her gift paid for my university education. And then, in 1998, Pfizer received FDA approval to sell Viagra.<\/p>\n
Pfizer initially developed the drug to treat high blood pressure and angina pectoris. However, as Pfizer\u2019s researchers discovered in clinical trials, the drug was better at inducing erections than managing angina. And so, the company repurposed the drug for erectile dysfunction and launched a massive, global PR and marketing campaign\u2014including seeking moral approval from Pope John Paul II and contracting the war hero and 1996 presidential candidate Bob Dole to be the brand\u2019s poster gentleman\u2014that succeeded in making Viagra a blockbuster.<\/p>\n
So, I learned why pharmaceutical companies seek to develop blockbuster drugs with fanatical zeal. Formulating a safe and effective new medicine to address a large, unmet need is very difficult and expensive. Performing clinical trials and obtaining FDA-approval is an arduous process that normally takes several years. Thus, if an opportunity for a new blockbuster presents itself, a big drug company like Pfizer will go to extreme lengths to seize it.<\/p>\n
Three years after the release of Viagra, I learned that Pfizer was not the respectable company my great grandmother had believed it to be. I arrived at this realization through my interest in British spy novels. In 2001 I lived in Vienna, around the corner from the Burgkino (Burg Cinema) which still played the 1949 film noir classic The Third Man <\/em>on its big screen every weekend. I spent many a dreary winter Sunday afternoon watching the film. Based on the novella and screenplay by Graham Greene, The Third Man <\/em>is a crime story about Harry Lime\u2014an American running a medical charity in Vienna, who makes a killing selling penicillin on the bombed out, impoverished city\u2019s black market. To increase his profits, he cuts the drug with other substances, thereby destroying its efficacy and causing the patients (including children) to die horribly from their infections.<\/p>\n In the film\u2019s most iconic scene, the good guy (played by Joseph Cotton) meets his old friend Harry Lime (played by Orson Welles) on the Giant Ferris wheel in the Vienna Prater amusement park and tries to appeal to his conscience. At the wheel\u2019s apex, the charismatic Harry opens the door, points down to people walking on the ground below, and says:<\/p>\n “Look down there. Would you really feel any pity if one of those dots stopped moving forever? If I offered you twenty thousand pounds for every dot that stopped, would you really, old man, tell me to keep my money, or would you calculate how many dots you could afford to spare? Free of income tax, old man. Free of income tax. … Nobody thinks in terms of human beings. Governments don\u2019t, why should we? They talk about the people and the proletariat; I talk about the suckers and the mugs. It\u2019s the same thing. They have their five-year plans, and so have I.”<\/p>\n I sensed that Graham Greene might have based the story on something he\u2019d witnessed or heard about. Doing some research, I learned that Harry Lime was probably based on the British spy Harold \u201cKim\u201d Philby, with whom Greene worked in British intelligence during World War II. Greene, it seems, discovered that Philby was a Soviet double agent long before he was exposed as such in 1963. Instead of ratting out his friend, he kept it to himself and left the intelligence service in 1944. Several pieces of evidence suggest that when he wrote The Third Man <\/em>a few years later, he based it on his conflicted friendship with Philby.<\/p>\n John le Carre\u0301 was also fascinated by Graham Greene and Kim Philby, and his thriller Tinker, Tailor, Soldier, Spy\u2014<\/em>one of my all-time favorites\u2014<\/em>was inspired by the Philby story. His novel The Constant Gardener <\/em>was published in 2001, and I read it with great interest. The story wasn\u2019t set in Cold War Europe, but in Kenya, where a British diplomat\u2019s wife is brutally raped and murdered. Upon closer examination, the diplomat realizes that she was about to reveal a horrifying crime committed by a pharmaceutical company, which murdered her in order to prevent the exposure.<\/p>\n The novel\u2019s plot was reminiscent of a controversial drug trial performed by Pfizer in Kano, Nigeria in 1996 during a meningococcal outbreak. For the trial of its new antibiotic, trovafloxacin, Pfizer gave 100 children this new drug. The control group of 100 other children received the standard anti-meningitis treatment at the time\u2014a drug called ceftriaxone. However, for the control group, Pfizer administered a substantially lower dose of ceftriaxone than the drug\u2019s FDA-approved standard.<\/p>\n When the reduced dosing in the control group was discovered, it raised the suspicion that Pfizer did this in order to skew the trial in favor of its new drug. Five of the children who received trovafloxacin died, while six who received the reduced dose of ceftriaxone died. Other children apparently suffered grave injuries from the administration of the experimental antibiotic without their informed consent. The investigation and litigation that ensued was the stuff of a thriller, involving private investigators, bribery, blackmail attempts, and disappearing records. Thirteen years later, in 2009, Pfizer settled out of court with the plaintiffs.<\/p>\n In his author\u2019s note, le Carre\u0301 claimed that nobody and no corporation in the novel was based on an actual person or corporation in the real world.<\/p>\n “But I can tell you this. As my journey through the pharmaceutical jungle progressed, I came to realize that, by comparison with the reality, my story was as tame as a holiday postcard.”<\/p>\n In 2009, the same year that Pfizer settled with the trovafloxacin plaintiffs, the New York Times <\/em>reported that a U.S. federal judge assessed Pfizer with the \u201clargest health care fraud settlement and the largest criminal fine of any kind ever\u201d for its illegal marketing of Bextra and three other drugs. The U.S. Department of Justice was unequivocal in characterizing Pfizer\u2019s officers as guilty of grave criminal conduct at the expense of the American public.<\/p>\n As I have long known all of the above, I wasn\u2019t surprised by the gross criminal conduct revealed in The Pfizer Papers: Pfizer\u2019s Crimes Against Humanity<\/em>, edited by Naomi Wolf with Amy Kelly and a Foreword by Stephen K. Bannon. The 366-page hardcover book\u2014beautifully published by War Room Books, an imprint of Skyhorse Publishing, is a meticulous analysis of Pfizer documents the FDA was forced to release as a result of Aaron Siri\u2019s lawsuit.<\/p>\n The book strikes me as one of the most impressive works of investigative scholarship in history. As Dr. Peter McCullough described it in his Praise (printed on the book\u2019s first page):<\/p>\n “This is a comprehensive, organized, and compelling presentation of vaccine safety data that has accumulated after mass and indiscriminate administration of the Pfizer mRNA COVID-19 vaccines. Sadly, a large group of vaccine recipients have become injured, disabled, and many have died after the ill-advised injections. The data with histopathological evaluation at necropsy and autopsy with expert analysis is presented so you can evaluate it for yourself. Never before has there been a class of products with this wide range and extended duration of injury to the recipient.”<\/p>\n On Saturday, November 16, I attended the official launch of this magisterial work of what I believe falls squarely within the true crime genre of literature. It was a great honor for me to attend the gathering with the book\u2019s editors and authors. It seemed to me that I was witnessing history being made.<\/p>\n I strongly recommend the book to everyone in the world who is interested in truth and justice. The book should be required reading by everyone in the legislative and executive branches of the U.S. government, especially President-elect Trump\u2019s staff.<\/p>\n Please purchase your copy today by clicking on the image below. Producing the book was a Herculean effort. Never before have a book\u2019s authors and publisher been so deserving of compensation for their work. I agree with Dr. Peter Breggin\u2019s sentiment that they, as well as editor Naomi Wolf and project director Amy Kelly, \u201cshould get the Nobel Prize for medicine and the praises of a grateful humanity.\u201d<\/p>\n