{"id":57373,"date":"2024-10-07T12:16:31","date_gmt":"2024-10-07T01:16:31","guid":{"rendered":"https:\/\/www.tomgrimshaw.com\/tomsblog\/maintenance.html\/?p=57373"},"modified":"2024-10-07T12:16:31","modified_gmt":"2024-10-07T01:16:31","slug":"the-spike-protein-alone-induces-all-nine-hallmarks-of-aging","status":"publish","type":"post","link":"https:\/\/www.tomgrimshaw.com\/tomsblog\/?p=57373","title":{"rendered":"The Spike Protein Alone Induces All Nine Hallmarks of Aging"},"content":{"rendered":"<ol>\n<li>Genomic Instability<br \/>\nThe Spike Protein directly impairs DNA repair in the nucleus.<\/li>\n<li>Telomere Attrition<br \/>\nLess telomerase activity.<\/li>\n<li>Epigenetic Alterations<br \/>\nThe Spike Protein causes epigenetic alterations which assists in viral entry and pathogenesis.<\/li>\n<li>Deregulated Nutrient Sensing<br \/>\nDisrupts gut function and nutrient uptake and makes you feel fuller sooner.<\/li>\n<li>Loss of Proteostasis<br \/>\n(Protein homeostasis or proteostasis, the correct balance between production and degradation of proteins, is an essential pillar for proper cellular function.) Spike protein induces protein misfolding leading to Prion disease.<\/li>\n<li>Cellular Senescence<br \/>\nVirus infected or spike-transfected human epithelial (skin, lung and gut lining) cells showed increased senescence (<span data-v-76601ff2=\"\" data-v-20e78780=\"\">the condition or process of deterioration with age, <\/span><span data-v-76601ff2=\"\" data-v-20e78780=\"\">loss of a cell&#8217;s power of division and growth)<\/span><\/li>\n<li>Mitochondrial Dysfunction<br \/>\nDisrupts molecular signaling leading to mitochondrial damage and fragmentation.<\/li>\n<li>Stem Cell Exhaustion<br \/>\nDecreases stem cell growth and expansion.<\/li>\n<li>Altered Intercellular Communication<br \/>\nSpike protein promotes cell signaling without other all components.<\/li>\n<\/ol>\n<p><a href=\"https:\/\/wmcresearch.org\/hallmarks-of-aging-and-the-spike\/\">https:\/\/wmcresearch.org\/hallmarks-of-aging-and-the-spike\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Genomic Instability The Spike Protein directly impairs DNA repair in the nucleus. Telomere Attrition Less telomerase activity. Epigenetic Alterations The Spike Protein causes epigenetic alterations which assists in viral entry and pathogenesis. Deregulated Nutrient Sensing Disrupts gut function and nutrient uptake and makes you feel fuller sooner. Loss of Proteostasis (Protein homeostasis or proteostasis, the &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.tomgrimshaw.com\/tomsblog\/?p=57373\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;The Spike Protein Alone Induces All Nine Hallmarks of Aging&#8221;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5,6,133],"tags":[],"class_list":["post-57373","post","type-post","status-publish","format-standard","hentry","category-general-interest","category-health-tips","category-vaccines"],"_links":{"self":[{"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=\/wp\/v2\/posts\/57373","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=57373"}],"version-history":[{"count":1,"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=\/wp\/v2\/posts\/57373\/revisions"}],"predecessor-version":[{"id":57374,"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=\/wp\/v2\/posts\/57373\/revisions\/57374"}],"wp:attachment":[{"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=57373"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=57373"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=57373"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}