{"id":47800,"date":"2023-11-29T07:59:23","date_gmt":"2023-11-28T20:59:23","guid":{"rendered":"https:\/\/www.tomgrimshaw.com\/tomsblog\/?p=47800"},"modified":"2023-11-29T07:59:23","modified_gmt":"2023-11-28T20:59:23","slug":"how-glycine-fights-viruses","status":"publish","type":"post","link":"https:\/\/www.tomgrimshaw.com\/tomsblog\/?p=47800","title":{"rendered":"How Glycine Fights Viruses"},"content":{"rendered":"<section class=\"main-content\">\n<div class=\"max-width\">\n<div id=\"article\">\n<div id=\"bcr_Upanel\">\n<div id=\"bcr_UpdPnlStory\">\n<div id=\"bcr_pnlStoryAtAGlance\" class=\"story-glance\" data-swiftype-name=\"saag\" data-swiftype-type=\"text\">\n<div class=\"story-highlights\">\n<h3 id=\"expanderHead\" data-jsid=\"expanderHead\">STORY AT-A-GLANCE<\/h3>\n<div id=\"expanderContent\" data-jsid=\"expanderContent\">\n<ul>\n<li><span id=\"bcr_rptStory_cslStory_0\">Collagen accounts for about 30% of the total protein in your body; 28% of collagen, in turn, is made up of the amino acid glycine<\/span><\/li>\n<li><span id=\"bcr_rptStory_cslStory_1\">Glycine is the amino acid with the highest concentration in connective tissue. Its benefits go far beyond connective tissue health as glycine has anti-inflammatory effects, acts as a neurotransmitter, and plays an important role in the epigenetic regulation that drives the aging process<\/span><\/li>\n<li><span id=\"bcr_rptStory_cslStory_2\">Glycine helps protect against viruses by reinforcing the extracellular matrix, which acts as a physical barrier to infectious agents such as bacteria, fungi and viruses<\/span><\/li>\n<li><span id=\"bcr_rptStory_cslStory_3\">Most people need 8.5 to 10 grams more glycine than what their bodies can synthesize in a day<\/span><\/li>\n<li><span id=\"bcr_rptStory_cslStory_4\">To boost your glycine intake, either eat more collagen or gelatin-rich foods and take a high-quality collagen or gelatin supplement, or supplement with pure glycine, which is available in powder form and tends to be very affordable<\/span><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div id=\"bodytext\" class=\"bodytextdiv\" data-swiftype-name=\"postbody\" data-swiftype-type=\"text\">\n<p>Collagen accounts for about 30% of the total protein in your body; 28% of\u00a0<a href=\"https:\/\/takecontrol.substack.com\/p\/why-collagen-is-a-proven-necessity\" target=\"_blank\" rel=\"noopener\">collagen<\/a>, in turn, is made up of glycine, and it is the amino acid with the highest concentration in collagen.<sup><span id=\"edn1\" data-hash=\"#ednref1\">1<\/span><\/sup>\u00a0It is a mildly sweet amino acid that can also be used as a sugar substitute.<\/p>\n<p>Glycine, proline and hydroxyproline<sup><span id=\"edn2\" data-hash=\"#ednref2\">2<\/span><\/sup>\u00a0are the raw materials for connective tissue, but the benefits of glycine go far beyond connective tissue health. For example, glycine:<\/p>\n<div class=\"indent\">\n<p><span class=\"bullet\">\u2022<\/span>Has potent anti-inflammatory effects, in part by inhibiting activation of immune cells and suppressing the production of proinflammatory cytokines, and in part by inhibiting the consumption of nicotinamide adenine dinucleotide phosphate hydrogen (NADPH), as\u00a0<a href=\"https:\/\/takecontrol.substack.com\/p\/the-healthy-sugar-substitute-youve\" target=\"_blank\" rel=\"noopener\">detailed in this previous article<\/a>.<\/p>\n<p><span class=\"bullet\">\u2022<\/span>Plays an important role in the aging process. In some animal studies, diets containing 8% to 12% glycine increased the median lifespan by as much as 28.4%.<sup><span id=\"edn3\" data-hash=\"#ednref3\">3<\/span><\/sup><\/p>\n<p>According to previous research,<sup><span id=\"edn4\" data-hash=\"#ednref4\">4<\/span><\/sup>\u00a0glycine may even be responsible for the epigenetic regulation that drives the aging process as a whole. It also induces\u00a0<a href=\"https:\/\/takecontrol.substack.com\/p\/how-to-activate-autophagy\" target=\"_blank\" rel=\"noopener\">autophagy<\/a>, so that renewal and regeneration of your damaged cells can take place.<\/p>\n<p><span class=\"bullet\">\u2022<\/span>Is a precursor to glutathione, a powerful endogenous antioxidant that declines with age.<\/p>\n<p><span class=\"bullet\">\u2022<\/span>Acts as a neurotransmitter<sup><span id=\"edn5\" data-hash=\"#ednref5\">5<\/span><\/sup>\u00a0and may play an important role in depression.<sup><span id=\"edn6\" data-hash=\"#ednref6\">6<\/span><\/sup>\u00a0It\u2019s also been shown to alleviate neuroinflammation and protect against cognitive deficits in mice with neurodegeneration.<sup><span id=\"edn7\" data-hash=\"#ednref7\">7<\/span><\/sup><\/p>\n<div class=\"MidProductAd\"><\/div>\n<p><span class=\"bullet\">\u2022<\/span>Helps prevent cancer by inhibiting the growth of blood vessels that feed tumors.<sup><span id=\"edn8\" data-hash=\"#ednref8\">8<\/span><\/sup><\/p>\n<\/div>\n<h2>Glycine Protects Against Viral Infections<\/h2>\n<p>Interestingly, glycine also helps protect against viruses by reinforcing your extracellular matrix, as evidenced in a 2021 study.<sup><span id=\"edn9\" data-hash=\"#ednref9\">9<\/span><\/sup>\u00a0Collagen, which is high in glycine, is the primary protein of the extracellular matrix, which acts as a physical barrier against infectious agents such as bacteria, viruses and fungi.<\/p>\n<p>When you\u2019re deficient in glycine, your extracellular matrix is weakened, thereby raising the risk of viruses being able to proliferate through your tissues. Many infectious agents secrete proteases that destroy collagen to facilitate their proliferation.<\/p>\n<aside class=\"takeaway tamiddle\">Glycine intake at the afore-mentioned dose prevents the spread of viruses by strengthening the extracellular matrix barriers against their advance. ~ Journal of Functional Foods January 2021<\/p>\n<\/aside>\n<p>Some viruses are also known to inhibit collagen synthesis, which has the same effect.<sup><span id=\"edn10\" data-hash=\"#ednref10\">10<\/span><\/sup>\u00a0Making sure you have enough glycine in your system at all times can help prevent viruses from destroying enough collagen to get inside your cells.<\/p>\n<h2>Another Mechanism to Explain Glycine\u2019s Infection Protection<\/h2>\n<p>A 2020 study<sup><span id=\"edn11\" data-hash=\"#ednref11\">11<\/span><\/sup>\u00a0showed an antiviral mechanism for glycine in that it prevents for formation of capsids. You probably didn\u2019t know this, but viruses carry around an outer shell of proteins called a capsid. This capsid acts like a lockpick in that it attaches to and pries open the cell\u2019s membrane it is seeking to infect.<\/p>\n<div class=\"center-img\"><img decoding=\"async\" class=\" mlazyloaded\" src=\"https:\/\/media.mercola.com\/ImageServer\/public\/2023\/November\/glycine-capsid.jpg\" alt=\"glycine capsid\" data-mlazyload-src=\"https:\/\/media.mercola.com\/ImageServer\/public\/2023\/November\/glycine-capsid.jpg\" \/><\/div>\n<p>The virus then hijacks the cell\u2019s inner workings, forcing it to mass produce the virus\u2019s genetic material and construct many viral replicas. These capsids are like popcorn kernels pushing away the lid of an overfilled pot: The new viruses explode through the cell wall, and the cycle continues with more virus lockpicks on the loose.<\/p>\n<p>Since glycine prevents the viruses from forming a capsid, they become unstable and unable to infect other cells as they simply disintegrate without their capsid &#8220;shell.&#8221;<\/p>\n<h2>Glycine Supplementation Is a Necessity<\/h2>\n<p>While your body does synthesize glycine, there\u2019s a limit to how much your body can make, and more than likely it falls far short of your requirements to perform all of its essential functions. As explained by the authors:<sup><span id=\"edn12\" data-hash=\"#ednref12\">12<\/span><\/sup><\/p>\n<blockquote><p><em>&#8220;Glycine produced by human metabolism is much lower than the cell\u2019s needs, giving a general glycine deficiency of 10\u202fg\/day in humans. This effect was tested for three years in 127 volunteers who had virus infections usually once or more times every year.<\/em><\/p><\/blockquote>\n<blockquote><p><em>85 of them took glycine 10\u202fg\/day; 42 did not take glycine. Among those who took glycine, only 16 (12 of whom had infections two or more times each year) had the flu just in the first year \u2014 but much reduced in severity and duration \u2014 while those who did not take glycine, were infected as often and as severely as before.<\/em><\/p><\/blockquote>\n<blockquote><p><em>Glycine intake at the afore-mentioned dose prevents the spread of viruses by strengthening the extracellular matrix barriers against their advance &#8230;<\/em><\/p><\/blockquote>\n<blockquote><p><em>[G]lycine must be considered to be an essential or indispensable amino acid because, although it can be synthesized by human metabolism, the body\u2019s capacity for its synthesis does not satisfy the needs of the cells, especially for collagen synthesis. Neither can glycine be considered \u2018conditionally essential\u2019 as its need is a general requisite, independent of any particular circumstances.&#8221;<\/em><\/p><\/blockquote>\n<p>According to previous calculations<sup><span id=\"edn13\" data-hash=\"#ednref13\">13<\/span><\/sup>\u00a0that considered glycine\u2019s role in metabolism and the synthesis of metabolites, collagen and other proteins, most people need 8.5 to 10 grams more glycine than what their bodies can make in a day.<\/p>\n<p>As a result, the authors of the 2021 paper recommend daily supplementation at a dose of 10 grams a day &#8220;to prevent and solve health problems of the body\u2019s mechanical system such as osteoarthritis and osteoporosis,&#8221; and &#8220;the entire connective system of the extracellular matrix that is found in all tissues.&#8221;<sup><span id=\"edn14\" data-hash=\"#ednref14\">14<\/span><\/sup><\/p>\n<blockquote><p><em>&#8220;The close relationship we have shown here between the consistency and strength of the extracellular matrix, based on healthy collagen, and resistance to viruses highlights the need to maintain this structure in good condition, for which dietary glycine supplementation is necessary,&#8221;<\/em>\u00a0they note.<\/p><\/blockquote>\n<p>The authors also stress that glycine supplementation may be more important than vaccines, because:<\/p>\n<blockquote><p><em>&#8220;&#8230; vaccines are specific for a particular antigen, and continuous mutations of viruses &#8230; can alter their antigenic protein rapidly, rendering the vaccine ineffective in a short time. The enhancement of collagen in the extracellular matrix, however, will always be effective and steadfast against any invasive agent.&#8221;<\/em><\/p><\/blockquote>\n<h2>The Vitamin C Link<\/h2>\n<p>On a side note, the extracellular matrix\u2019s role in blocking infection helps explain why vitamin C is so effective against infections. In short, vitamin C plays a key role in collagen synthesis, so one of the ways in which it prevents and treats infection is by strengthening the extracellular matrix, just like glycine does.<\/p>\n<p>That said, vitamin C alone will not be as effective as when taken in conjunction with glycine. As explained by the authors:<sup><span id=\"edn15\" data-hash=\"#ednref15\">15<\/span><\/sup><\/p>\n<blockquote><p><em>&#8220;Ascorbate contributes to precise collagen synthesis by avoiding or eliminating collateral reactions in proline and lysine hydroxylation, but it cannot cover the need for glycine, which must be ingested additionally to make possible the synthesis and renewal of collagen necessary to maintain firm extracellular matrix.&#8221;<\/em><\/p><\/blockquote>\n<h2>Glycine With NAC Supports Mitochondrial Health<\/h2>\n<p>Another nutrient that has important synergistic effects with glycine is N-acetylcysteine (NAC). Like glycine, NAC is a precursor to glutathione, and when taken together, they can go a long way toward protecting your mitochondrial health.<\/p>\n<p>For example, researchers at Baylor College of Medicine have shown<sup><span id=\"edn16\" data-hash=\"#ednref16\">16<\/span><\/sup>\u00a0that glycine and NAC supplementation not only improves glutathione deficiency but also mitochondrial impairment, oxidative stress and insulin resistance in older mice.<\/p>\n<p>Similar results have also been found in seniors (by the same team). Importantly, in the elderly, supplementation with glycine and NAC improved four of nine hallmarks of aging associated with most age-related disorders, namely mitochondrial dysfunction, inflammation, insulin resistance and genomic damage.<\/p>\n<h2>Glycine Protects Against Chronic Disease and Disability<\/h2>\n<p>Glycine supplementation makes loads of sense when you consider its role in mitigating chronic disease and disability. As reported in a 2023 scientific review, glycine has been shown to:<sup><span id=\"edn17\" data-hash=\"#ednref17\">17<\/span><\/sup><\/p>\n<table class=\"generic-table left-align\">\n<tbody>\n<tr>\n<td valign=\"top\">Suppress tumor growth in mice with melanoma<sup><span id=\"edn18\" data-hash=\"#ednref18\">18<\/span><\/sup><\/td>\n<td valign=\"top\">Decrease fasting glucose, insulin, triglyceride and IGF-1 in male rats<sup><span id=\"edn19\" data-hash=\"#ednref19\">19<\/span><\/sup><\/td>\n<\/tr>\n<tr>\n<td valign=\"top\">Preserve muscle mass and reduce inflammatory markers in mice with cancer cachexia<sup><span id=\"edn20\" data-hash=\"#ednref20\">20<\/span><\/sup><\/td>\n<td valign=\"top\">Improve endothelial function in older rats<sup><span id=\"edn21\" data-hash=\"#ednref21\">21<\/span><\/sup><\/td>\n<\/tr>\n<tr>\n<td valign=\"top\">Reduce weight gain and improve bone mineral density in a mouse model designed to mimic postmenopausal bone loss<sup><span id=\"edn22\" data-hash=\"#ednref22\">22<\/span><\/sup><\/td>\n<td valign=\"top\">Protect against cardiac hypertrophy<sup><span id=\"edn23\" data-hash=\"#ednref23\">23<\/span><\/sup><\/td>\n<\/tr>\n<tr>\n<td valign=\"top\">Alleviate neuroinflammation and protect against cognitive deficits in mice with neurodegeneration<sup><span id=\"edn24\" data-hash=\"#ednref24\">24<\/span><\/sup><\/td>\n<td class=\"hide-mobile\"><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Researchers have also noted that supplemental glycine may be useful for the &#8220;prevention and control of atherosclerosis, heart failure, angiogenesis associated with cancer or retinal disorders and a range of inflammation-driven syndromes, including metabolic syndrome.&#8221;<sup><span id=\"edn25\" data-hash=\"#ednref25\">25<\/span><\/sup><\/p>\n<p>In his article &#8220;Gelatin, Stress, Longevity,&#8221;<sup><span id=\"edn26\" data-hash=\"#ednref26\">26<\/span><\/sup>\u00a0the late Ray Peat, a biologist and pioneer of bioenergetic medicine,<sup><span id=\"edn27\" data-hash=\"#ednref27\">27<\/span><\/sup>\u00a0also reviewed a long list of health conditions that can be prevented or alleviated by glycine supplementation and\/or increased consumption of collagen or gelatin, including:<sup><span id=\"edn28\" data-hash=\"#ednref28\">28<\/span><\/sup><\/p>\n<table class=\"generic-table left-align\">\n<tbody>\n<tr>\n<td valign=\"top\">Fibrosis<\/td>\n<td valign=\"top\">Most bleeding problems, including nosebleeds, excessive menstrual bleeding, bleeding ulcers, hemorrhoids and stroke. According to Peat, glycine, taken shortly after a stroke, limits the damage and accelerates recovery<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\">Epilepsy, by stabilizing nerves and raising the amount of stimulation required to activate nerves<\/td>\n<td valign=\"top\">Multiple sclerosis (MS), thanks to its antispastic effects<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\">Any condition involving excess prolactin, serotonin and\/or cortisol, including autism, postpartum and premenstrual problems, Cushing&#8217;s disease, diabetes, and impotence<\/td>\n<td valign=\"top\">Muscular dystrophy and myasthenia gravis<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\">Metabolic disorders<sup><span id=\"edn29\" data-hash=\"#ednref29\">29<\/span><\/sup><\/td>\n<td valign=\"top\">Nonalcoholic fatty liver disease (NAFLD)<sup><span id=\"edn30\" data-hash=\"#ednref30\">30<\/span><\/sup><\/td>\n<\/tr>\n<tr>\n<td valign=\"top\"><a href=\"https:\/\/takecontrol.substack.com\/p\/glycine-increase-longevity-decrease-depression\" target=\"_blank\" rel=\"noopener\">Depression<\/a>\u00a0and schizophrenia<sup><span id=\"edn31\" data-hash=\"#ednref31\">31<\/span><\/sup><\/td>\n<td class=\"hide-mobile\"><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Other health benefits of glycine include:<\/p>\n<ul>\n<li>Improved sleep<sup><span id=\"edn32\" data-hash=\"#ednref32\">32<\/span><\/sup><\/li>\n<li>Reduced stress<sup><span id=\"edn33\" data-hash=\"#ednref33\">33<\/span><\/sup><\/li>\n<li>Improved wound healing<sup><span id=\"edn34\" data-hash=\"#ednref34\">34<\/span><\/sup><\/li>\n<li>Improved gut health<sup><span id=\"edn35\" data-hash=\"#ednref35\">35<\/span><\/sup><\/li>\n<\/ul>\n<h2>How to Optimize Your Glycine Intake<\/h2>\n<p>Considering its many benefits, making sure you get enough glycine in your diet can go a long way toward improving your health and life span, and there are several ways you can do that:<\/p>\n<ol>\n<li>Eat more collagen or gelatin-rich foods, as glycine makes up nearly one-third of collagen and gelatin. Examples include homemade bone broth made with bones and connective tissue from grass fed, organically raised animals, and chicken broth made from organic chicken feet. The claws are particularly rich in collagen.<sup><span id=\"edn36\" data-hash=\"#ednref36\">36<\/span><\/sup><\/li>\n<li>Take a high-quality collagen or gelatin supplement.<\/li>\n<li>Take a glycine supplement. Pure glycine is available in powder form and tends to be very affordable and easy to take, as it has a mildly sweet flavor.<\/li>\n<\/ol>\n<p>Indirectly, animal foods such as seafood, red meat, poultry and dairy products will also raise your glycine level, as these foods contain\u00a0<a href=\"https:\/\/takecontrol.substack.com\/p\/taurine-for-longevity-and-healthier-lifespan\" target=\"_blank\" rel=\"noopener\">taurine<\/a>, which increases glycine.<sup><span id=\"edn37\" data-hash=\"#ednref37\">37<\/span><\/sup>\u00a0That said, don\u2019t rely on red meat for your glycine. As you can see from the chart below, beef contains only a fraction of the glycine you get from gelatin and collagen. You simply cannot get enough glycine from beef alone.<\/p>\n<div class=\"center-img\"><img decoding=\"async\" class=\" mlazyloaded\" src=\"https:\/\/media.mercola.com\/ImageServer\/public\/2023\/August\/amino-acid-table.jpg\" alt=\"amino acid\" data-mlazyload-src=\"https:\/\/media.mercola.com\/ImageServer\/public\/2023\/August\/amino-acid-table.jpg\" \/><\/div>\n<h2>Dosing Suggestions<\/h2>\n<p>While there\u2019s no established daily requirement or upper limit of glycine, as previously noted, most people tend to be about 10 grams short of what their bodies need for their daily metabolic processes,<sup><span id=\"edn38\" data-hash=\"#ednref38\">38<\/span><\/sup>\u00a0so that\u2019s probably a good goalpost.<\/p>\n<p>Another study looking at people with metabolic syndrome found 15 grams of glycine a day for three months reduced oxidative stress and improved systolic blood pressure.<sup><span id=\"edn39\" data-hash=\"#ednref39\">39<\/span><\/sup><\/p>\n<p>You can\u2019t overdose on glycine, so a daily dose of 10 to 20 grams would probably be an ideal range for most people. If you have any of the chronic health problems reviewed above, or are elderly or frail, you\u2019d probably want to lean toward the higher dosages.<\/p>\n<p>From Dr Joseph Mercola&#8217;s site Mercola.com<\/p>\n<\/div>\n<div class=\"social-icons-bottom narrow-width\">\n<p><a role=\"link\" href=\"https:\/\/www.facebook.com\/sharer\/sharer.php?u=https%3A%2F%2Farticles.mercola.com%2Fsites%2Farticles%2Farchive%2F2023%2F11%2F27%2Fhow-glycine-fights-viruses.aspx%3Fui%3D3b72fa71e5f1317e30d882e63ba33833c501a09b553937da5fcc7736d8e1c7e9%26sd%3D20210307%26cid_source%3Ddnl%26cid_medium%3Demail%26cid_content%3Dart1ReadMore%26cid%3D20231127Z1_NB%26foDate%3Dfalse%26mid%3DDM1496624%26rid%3D1977327208\" name=\"Facebook Page\" aria-label=\"Facebook Page\"><\/a><\/p>\n<div class=\"social-sticky\">\n<p><a href=\"https:\/\/www.facebook.com\/sharer\/sharer.php?u=https%3A%2F%2Farticles.mercola.com%2Fsites%2Farticles%2Farchive%2F2023%2F11%2F27%2Fhow-glycine-fights-viruses.aspx%3Fui%3D3b72fa71e5f1317e30d882e63ba33833c501a09b553937da5fcc7736d8e1c7e9%26sd%3D20210307%26cid_source%3Ddnl%26cid_medium%3Demail%26cid_content%3Dart1ReadMore%26cid%3D20231127Z1_NB%26foDate%3Dfalse%26mid%3DDM1496624%26rid%3D1977327208\" name=\"Facebook Page\" aria-label=\"Facebook Page\"><\/a><\/p>\n<\/div>\n<\/div>\n<div id=\"bcr_divfootnote\" class=\"sources-references narrow-width\"><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n<div class=\"footer-content\">\n<footer class=\"footer\" data-js-cat-display=\"disclaimer\">\n<div class=\"max-width\">\n<div class=\"footer-links\"><\/div>\n<\/div>\n<\/footer>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>STORY AT-A-GLANCE Collagen accounts for about 30% of the total protein in your body; 28% of collagen, in turn, is made up of the amino acid glycine Glycine is the amino acid with the highest concentration in connective tissue. Its benefits go far beyond connective tissue health as glycine has anti-inflammatory effects, acts as a &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.tomgrimshaw.com\/tomsblog\/?p=47800\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;How Glycine Fights Viruses&#8221;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5,6],"tags":[],"class_list":["post-47800","post","type-post","status-publish","format-standard","hentry","category-general-interest","category-health-tips"],"_links":{"self":[{"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=\/wp\/v2\/posts\/47800","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=47800"}],"version-history":[{"count":1,"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=\/wp\/v2\/posts\/47800\/revisions"}],"predecessor-version":[{"id":47801,"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=\/wp\/v2\/posts\/47800\/revisions\/47801"}],"wp:attachment":[{"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=47800"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=47800"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=47800"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}