{"id":26502,"date":"2020-02-08T16:34:26","date_gmt":"2020-02-08T05:34:26","guid":{"rendered":"http:\/\/www.tomgrimshaw.com\/tomsblog\/?p=26502"},"modified":"2020-02-08T16:34:26","modified_gmt":"2020-02-08T05:34:26","slug":"effectiveness-of-hpv-vaccines-cervarix-and-gardasil-under-question","status":"publish","type":"post","link":"https:\/\/www.tomgrimshaw.com\/tomsblog\/?p=26502","title":{"rendered":"Effectiveness of HPV vaccines Cervarix and Gardasil under question"},"content":{"rendered":"\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"750\" height=\"500\" src=\"https:\/\/www.tomgrimshaw.com\/tomsblog\/wp-content\/uploads\/2020\/02\/HPV-Vaccine-image.jpg\" alt=\"Effectiveness of HPV vaccines Cervarix and Gardasil under question\" class=\"wp-image-26503\" srcset=\"https:\/\/www.tomgrimshaw.com\/tomsblog\/wp-content\/uploads\/2020\/02\/HPV-Vaccine-image.jpg 750w, https:\/\/www.tomgrimshaw.com\/tomsblog\/wp-content\/uploads\/2020\/02\/HPV-Vaccine-image-300x200.jpg 300w\" sizes=\"auto, (max-width: 706px) 89vw, (max-width: 767px) 82vw, 740px\" \/><\/figure>\n\n\n\n<p>Researchers analysing the design of HPV vaccines Cervarix and Gardasil efficacy trials found the Phase II and III trials had methodological problems that could have overstated the effectiveness of these vaccines against HPV.<\/p>\n\n\n\n<p>We found insufficient data to clearly conclude that HPV vaccine prevents the higher-grade abnormal cell changes\u201d<\/p>\n\n\n\n<p>The researchers from Newcastle University and Queen Mary University of London, both UK, found that the trials were not designed to detect cervical cancer because it takes decades to develop; instead they detected low grade abnormal cell changes. These changes, according to the study collaborators, are not clinically important because \u201cthey often resolve spontaneously without progressing,\u201d into cancers.<\/p>\n\n\n\n<p>\u201cWe found insufficient data to clearly conclude that HPV vaccine prevents the higher-grade abnormal cell changes that can eventually develop into cervical cancer,\u201d said Dr Claire Rees, Lead researcher from the Queen Mary University of London.<\/p>\n\n\n\n<p><a href=\"https:\/\/www.europeanpharmaceuticalreview.com\/news\/111334\/effectiveness-of-hpv-vaccines-cervarix-and-gardasil-under-question\/\">https:\/\/www.europeanpharmaceuticalreview.com\/news\/111334\/effectiveness-of-hpv-vaccines-cervarix-and-gardasil-under-question\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers analysing the design of HPV vaccines Cervarix and Gardasil efficacy trials found the Phase II and III trials had methodological problems that could have overstated the effectiveness of these vaccines against HPV. We found insufficient data to clearly conclude that HPV vaccine prevents the higher-grade abnormal cell changes\u201d The researchers from Newcastle University and &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.tomgrimshaw.com\/tomsblog\/?p=26502\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Effectiveness of HPV vaccines Cervarix and Gardasil under question&#8221;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5,6],"tags":[],"class_list":["post-26502","post","type-post","status-publish","format-standard","hentry","category-general-interest","category-health-tips"],"_links":{"self":[{"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=\/wp\/v2\/posts\/26502","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=26502"}],"version-history":[{"count":1,"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=\/wp\/v2\/posts\/26502\/revisions"}],"predecessor-version":[{"id":26504,"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=\/wp\/v2\/posts\/26502\/revisions\/26504"}],"wp:attachment":[{"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=26502"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=26502"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=26502"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}