{"id":17314,"date":"2017-10-16T21:23:36","date_gmt":"2017-10-16T11:23:36","guid":{"rendered":"http:\/\/tomgrimshaw.com\/tomsblog\/?p=17314"},"modified":"2024-06-28T03:14:01","modified_gmt":"2024-06-27T17:14:01","slug":"science-got-it-wrong","status":"publish","type":"post","link":"https:\/\/www.tomgrimshaw.com\/tomsblog\/?p=17314","title":{"rendered":"Science Got It Wrong"},"content":{"rendered":"<p>Shared from a friend on Facebook&#8230;<br \/>\nAs the vaccine worshippers keep claiming &#8220;science says so&#8221; and proceed to try and shut down or discredit people by throwing around phrases like &#8220;I believe Science over Google&#8221; (a search engine to access the world&#8217;s largest library by the way) I thought this would interest them. Below is a list of drugs firstly approved due to &#8220;Science&#8221; stating they were safe and then later withdrawn because they were hurting so many people and in some cases killing them, they had no choice because they were held accountable. The &#8220;science&#8221; was actually wrong!! The cost of doing business is the old saying. But of course all the vaccines are perfectly safe because &#8220;Science&#8221; says so!<\/p>\n<p>Alatrofloxacin 2006 Worldwide Liver toxicity; serious liver injury leading to liver transplant; death.<br \/>\nAlclofenac 1979 UK Vasculitis, Rash.<br \/>\nAlpidem (Ananxyl) 1995 Worldwide Not approved in the US, withdrawn in France in 1994 and the rest of the market in 1995 because of rare but serious hepatotoxicity.<br \/>\nAlosetron (Lotronex) 2000 US Serious gastrointestinal adverse events; ischemic colitis; severe constipation. Reintroduced 2002 on a restricted basis<br \/>\nAlthesin (=Alphaxolone amineptine + Alphadolone) 1984 France, Germany, UK Anaphylaxis.<br \/>\nAmineptine (Survector) 1999 France, US Hepatotoxicity, dermatological side effects, and abuse potential. Reason:<br \/>\nAminopyrine 1999 France, Thailand risk of agranulocytosis; severe acne.<br \/>\nAmobarbital 1980 Norway Self poisoning.<br \/>\nAmoproxan 1970 France Dermatologic and ophthalmic toxicity.<br \/>\nAnagestone acetate 1969 Germany Animal carcinogenicity.<br \/>\nAntrafenine 1984 France Unspecific experimental toxicity.<br \/>\nAprotinin (Trasylol) 2008 US Increased risk of death.<br \/>\nArdeparin (Normiflo) 2001 US Not for reasons of safety or efficacy.<br \/>\nAstemizole (Hismanal) 1999 US, Malaysia, Multiple Nonspecified Markets Fatal arrhythmia<br \/>\nAzaribine 1976 US Thromboembolism.<br \/>\nBendazac 1993 Spain Hepatotoxicity.<br \/>\nBenoxaprofen 1982 Germany, Spain, UK, US Liver and kidney failure; gastrointestinal bleeding; ulcers.<br \/>\nBenzarone 1992 Germany Hepatitis.<br \/>\nBenziodarone 1964 France, UK Jaundice.<br \/>\nBeta-ethoxy-lacetanilanide 1986 Germany Renal toxicity, animal carcinogenicity.<br \/>\nBezitramide 2004 Netherlands Fatal overdose.<br \/>\nBithionol 1967 US Dermatologic toxicity.<br \/>\nBroazolam 1989 UK Animal carcinogenicity.<br \/>\nBromfenac 1998 US Severe hepatitis and liver failure (some requiring transplantation).<br \/>\nBucetin 1986 Germany Renal toxicity.<br \/>\nBuformin 1978 Germany Metabolic toxicity.<br \/>\nBunamiodyl 1963 Canada, UK, US Nephropathy.<br \/>\nButamben (Efocaine)(Butoforme) 1964 US Dermatologic toxicity; psychiatric Reactions.<br \/>\nCanrenone 1986 Germany Animal Carcinogenicity.<br \/>\nCerivastatin (Baycol, Lipobay) 2001 US Risk of rhabdomyolysis<br \/>\nChlormadinone (Chlormenadione) 1970 UK, US Animal Carcinogenicity.<br \/>\nChlormezanone (Trancopal) 1996 European Union, US, South Africa, Japan Hepatotoxicity; Steven-Johnson Syndrome; Toxic Epidermal Necrolysis.<br \/>\nChlorphentermine 1969 Germany Cardiovascular Toxicity.<br \/>\nCianidanol 1985 France, Germany, Spain, Sweden Hemolytic Anemia.<br \/>\nCinepazide 1988 Spain Agranulocytosis.<br \/>\nCisapride (Propulsid) 2000 US Risk of fatal cardiac arrhythmias<br \/>\nClioquinol 1973 France, Germany, UK, US Neurotoxicity.<br \/>\nClobutinol 2007 Germany Ventricular arrhythmia, QT-prolongation.<br \/>\nCloforex 1969 Germany Cardiovascular toxicity.<br \/>\nClomacron 1982 UK Hepatotoxicity.<br \/>\nClometacin 1987 France Hepatotoxicity.<br \/>\nCo-proxamol (Distalgesic) 2004 UK Overdose dangers.<br \/>\nCyclobarbital 1980 Norway Self poisoning.<br \/>\nCyclofenil 1987 France Hepatotoxicity.<br \/>\nDantron 1963 Canada, UK, US Genotoxicity. withdrawn from general use in UK but permitted in terminal patients<br \/>\nDexfenfluramine 1997 European Union, UK, US Cardiac valvular disease.<br \/>\nPropoxyphene (Darvocet\/Darvon) 2010 Worldwide Increased risk of heart attacks and stroke.<br \/>\nDiacetoxydiphenolisatin 1971 Australia Hepatotoxicity.<br \/>\nDiethylstilbestrol 1970s Risk of teratogenicity<br \/>\nDifemerine 1986 Germany Multi-Organ toxicities.<br \/>\nDihydrostreptomycin 1970 US Neuropsychiatric reaction.<br \/>\nDilevalol 1990 UK Hepatotoxicity.<br \/>\nDimazole (Diamthazole) 1972 France, US Neuropsychiatric reaction.<br \/>\nDimethylamylamine (DMAA) 1983 US Voluntarily withdrawn from market by Lily.: Reintroduced as a dietary supplement in 2006; and in 2013 the FDA started work to ban it due to cardiovascular problems<br \/>\nDinoprostone 1990 UK Uterine hypotonus, fetal distress.<br \/>\nDipyrone(Metamizole) 1975 UK, US, Others Agranulocytosis, anaphylactic reactions.<br \/>\nDithiazanine iodide 1964 France, US Cardiovascular and metabolic reaction.<br \/>\nDofetilide 2004 Germany Drug interactions, prolonged QT.<br \/>\nDrotrecogin alfa (Xigris) 2011 Worldwide Lack of efficacy as shown by PROWESS-SHOCK study<br \/>\nEbrotidine 1998 Spain Hepatotoxicity.<br \/>\nEfalizumab (Raptiva) 2009 Germany Withdrawn because of increased risk of progressive multifocal leukoencephalopathy<br \/>\nEncainide 1991 UK, US Ventricular arrhythmias.<br \/>\nEthyl carbamate 1963 Canada, UK, US, Carcinogenicity.<br \/>\nEtretinate 1989 France Withdrawn US (1999). Risk for birth defects.<br \/>\nExifone 1989 France Hepatotoxicity.<br \/>\nFen-phen (popular combination of fenfluramine and phentermine) 1997 Cardiotoxicity<br \/>\nFenclofenac 1984 UK Cutaneous reactions; animal carcinogenicity.<br \/>\nFenclozic acid 1970 UK, US Jaundice, elevated hepatic enzymes.<br \/>\nFenfluramine 1997 European Union, UK, US, India, South Africa, others Cardiac valvular disease, pulmonary hypertension, cardiac fibrosis.<br \/>\nFenoterol 1990 New Zealand Asthma mortality.<br \/>\nFeprazone 1984 Germany, UK Cutaneous reaction, multiorgan toxicity.<br \/>\nFipexide 1991 France Hepatotoxicity.<br \/>\nFlosequinan (Manoplax) 1993 UK, US Increased mortality at higher doses; increased hospitalizations.<br \/>\nFlunitrazepam 1991 France Abuse.<br \/>\nGatifloxacin 2006 US Increased risk of dysglycemia.<br \/>\nGemtuzumab ozogamicin (Mylotarg) 2010 US No improvement in clinical benefit; risk for death.<br \/>\nGlafenine 1984 France, Germany Anaphylaxis.<br \/>\nGrepafloxacin (Raxar) 1999 Withdrawn Germany, UK, US others Cardiac repolarization; QT interval prolongation.<br \/>\nHydromorphone (Palladone, extended release version) 2005 High risk of accidental overdose when extended release version (Palladone) administered with alcohol. Standard hydromorphone is sold in most of the world including the US<br \/>\nIbufenac 1968 UK Hepatotoxicity, jaundice.<br \/>\nIndalpine 1985 France Agranulocytosis.<br \/>\nIndoprofen 1983 Germany, Spain, UK Animal carcinogenicity, gastrointestinal toxicity.<br \/>\nIodinated casein strophantin 1964 US Metabolic reaction.<br \/>\nIproniazid 1964 Canada Interactions with food products containing tyrosine.<br \/>\nIsaxonine phosphate 1984 France Hepatotoxicity.<br \/>\nIsoxicam 1983 France, Germany, Spain, others Stevens johnson syndrome.<br \/>\nKava Kava 2002 Germany Hepatotoxicity.<br \/>\nKetorolac 1993 France, Germany, others Hemorrhage, renal Failure.<br \/>\nL-tryptophan 1989 Germany, UK Eosinophilic myalgia syndrome.Still sold in the US<br \/>\nLevamisole (Ergamisol) 1999 US Still used as veterinary drug and as a human antihelminthic in many markets; listed on the WHO List of Essential Medicines. In humans, it was used to treat melanoma before it was withdrawn for agranulocytosis.<br \/>\nLevomethadyl acetate 2003 US Cardiac arrhythmias and cardiac arrest.<br \/>\nLumiracoxib (Prexige) 2007\u20132008 Worldwide Liver damage<br \/>\nLysergic acid diethylamide (LSD) 1950s\u20131960s Marketed as a psychiatric drug; withdrawn after it became widely used recreationally. Now illegal in most of the world.<br \/>\nMebanazine 1975 UK Hepatotoxicity, drug intereaction.<br \/>\nMethandrostenolone 1982 France, Germany, UK, US, others Off-label abuse.<br \/>\nMethapyrilene 1979 Germany, UK, US Animal carcinogenicity.<br \/>\nMethaqualone 1984 South Africa (1971), India (1984), United Nations (1971-1988) Withdrawn because of risk of addiction and overdose<br \/>\nMetipranolol 1990 UK, others Uveitis.<br \/>\nMetofoline 1965 US Unspecific experimental toxicity.<br \/>\nMibefradil 1998 European Union, Malaysia, US, others Fatal arrhythmia, drug interactions.<br \/>\nMinaprine 1996 France Convulsions.<br \/>\nMoxisylyte 1993 France Necrotic hepatitis.<br \/>\nMuzolimine 1987 France, Germany, European Union Polyneuropathy.<br \/>\nNatalizumab (Tysabri) 2005\u20132006 US Voluntarily withdrawn from US market because of risk of Progressive multifocal leukoencephalopathy (PML). Returned to market July, 2006.<br \/>\nNefazodone 2007 US, Canada, others Branded version withdrawn by originator in several countries in 2007 for hepatotoxicity. Generic versions available.<br \/>\nNialamide 1974 UK, US Hepatotoxicity, drug intereaction.<br \/>\nNikethamide 1988 multiple markets CNS Stimulation.<br \/>\nNitrefazole 1984 Germany Hepatic and hematologic toxicity.<br \/>\nNomifensine 1981-1986 France, Germany, Spain, UK, US, others Hemolytic Anemia, hepatotoxicity, serious hypersensitive reactions.<br \/>\nOxeladin 1976 Canada, UK, US (1976) Carcinogenicity.<br \/>\nOxyphenbutazone 1984-1985 UK, US, Germany, France, Canada Bone marrow suppression, Steven Johnson Syndrome.<br \/>\nOxyphenisatin (Phenisatin) Australia, France, Germany, UK, US Hepatotoxicity.<br \/>\nOzogamicin 2010 US No improvement in clinical benefit; risk for death; veno-occlusive disease.<br \/>\nPemoline (Cylert) 1997 Canada, UK Withdrawn from US in 2005. Hepatotoxicity Reason:hepatotoxicity.<br \/>\nPentobarbital 1980 Norway Self poisoning.<br \/>\nPentylenetetrazol 1982 Withdrawn for inability to produce effective convulsive therapy, and for causing seizures.<br \/>\nPergolide (Permax) 2007 US Risk for heart valve damage.<br \/>\nPerhexilene 1985 UK, Spain Neurologic and hepatic toxicity.<br \/>\nPhenacetin 1975 Canada An ingredient in &#8220;A.P.C.&#8221; tablet; withdrawn because of risk of cancer and kidney disease Germany Denmark, UK, US, others Reason: nephropathy.<br \/>\nPhenformin and Buformin 1977 France, Germany US Severe lactic acidosis[3]<br \/>\nPhenolphthalein 1997 US Carcinogenicity.<br \/>\nPhenoxypropazine 1966 UK Hepatotoxicity, drug intereaction.<br \/>\nPhenylbutazone 1985 Germany Off-label abuse, hematologic toxicity.<br \/>\nPhenylpropanolamine(Propagest, Dexatrim) 2000 Canada, US Hemorrhagic stroke.<br \/>\nPifoxime (=Pixifenide) 1976 France Neuropsychiatric reaction.<br \/>\nPirprofen 1990 France, Germany, Spain Liver toxicity.:223<br \/>\nPrenylamine 1988 Canada, France, Germany, UK, US, others Cardiac arrythmia and death.<br \/>\nProglumide 1989 Germany Respiratory reaction.<br \/>\nPronethalol 1965 UK Animal carcinogenicity.<br \/>\nPropanidid 1983 UK Allergy.<br \/>\nProxibarbal 1998 Spain, France, Italy, Portugal, Turkey Immunoallergic, thrombocytopenia.<br \/>\nPyrovalerone 1979 France Abuse.<br \/>\nRapacuronium (Raplon) 2001 US, multiple markets Withdrawn in many countries because of risk of fatal bronchospasm<br \/>\nRemoxipride 1993 UK, others Aplastic anemia.<br \/>\nRimonabant (Acomplia) 2008 Worldwide Risk of severe depression and suicide<br \/>\nRofecoxib (Vioxx) 2004 Worldwide withdrawn by MAH. Risk of myocardial infarction and stroke<br \/>\nRosiglitazone (Avandia) 2010 Europe Risk of heart attacks and death. This drug continues to be available in the US<br \/>\nSecobarbital France, Norway, others. Self poisoning.<br \/>\nSertindole 1998 European Union Arrhythmia and sudden cardiac death<br \/>\nSibutramine (Reductil\/Meridia) 2010 Australia, Canada,China, the European Union (EU), Hong Kong, India, Mexico, New Zealand, the Philippines, Thailand, the United Kingdom,and the United States Increased risk of heart attack and stroke.<br \/>\nSitaxentan 2010 Germany Hepatotoxicity.<br \/>\nSorivudine 1993 Japan Drug interaction and deaths.<br \/>\nSparfloxacin 2001 US QT prolongation and phototoxicity.<br \/>\nSulfacarbamide 1988 Germany Dermatologic, hematologic and hepatic reactions.<br \/>\nSulfamethoxydiazine 1988 Germany Unknown.<br \/>\nSulfamethoxypyridazine 1986 UK Dermatologic and hematologic reactions<br \/>\nSuloctidyl 1985 Germany, France, Spain Hepatotoxicity.<br \/>\nSuprofen 1986-1987 UK, Spain, US Flank pain, decreased kidney function.<br \/>\nTegaserod (Zelnorm) 2007 US Risk for heart attack, stroke, and unstable angina. Was available through a restricted access program until April 2008.<br \/>\nTemafloxacin 1992 Germany, UK, US, others Low blood sugar; hemolytic anemia; kidney, liver dysfunction; allergic reactions<br \/>\nTemafloxacin 1992 US Allergic reactions and cases of hemolytic anemia, leading to three patient deaths.<br \/>\nTemazepam (Restoril, Euhypnos, Normison, Remestan, Tenox, Norkotral) 1999 Sweden, Norway Diversion, abuse, and a relatively high rate of overdose deaths in comparison to other drugs of its group. This drug continues to be available in most of the world including the US, but under strict controls.<br \/>\nTerfenadine (Seldane, Triludan) 1997-1998 France, South Africa, Oman, others, US Prolonged QT interval; ventricular tachycardia<br \/>\nTerodiline (Micturin) 1991 Germany, UK, Spain, others Prolonged QT interval, ventricular tachycardia and arrhythmia.<br \/>\nTetrazepam 2013 European Union Serious cutaneous reactions<br \/>\nThalidomide 1961 Germany Withdrawn because of risk of teratogenicity; returned to market for use in leprosy and multiple myeloma under FDA orphan drug rules<br \/>\nThenalidine 1960 Canada, UK, US Neutropenia<br \/>\nThiobutabarbitone 1993 Germany Renal insufficiency.<br \/>\nThioridazine (Melleril) 2005 Germany, UK Withdrawn worldwide due to severe cardiac arrhythmias<br \/>\nTicrynafen(Tienilic acid) 1980 Germany, France, UK, US others Liver toxicity and death.<br \/>\nTolcapone (Tasmar) 1998 European Union, Canada, Australia Hepatotoxicity<br \/>\nTolrestat (Alredase) 1996 Argentina, Canada, Italy, others Severe hepatotoxicity<br \/>\nTriacetyldiphenolisatin 1971 Australia Hepatotoxicity.<br \/>\nTriazolam 1991 France, Netherlands, Finland, Argentina, UK others Psychiatric adverse drug reactions, amnesia.<br \/>\nTriparanol 1962 France, US Cataracts, alopecia, ichthyosis.<br \/>\nTroglitazone (Rezulin) 2000 US, Germany Hepatotoxicity<br \/>\nTrovafloxacin (Trovan) 1999-2001 European Union, US Withdrawn because of risk of liver failure<br \/>\nValdecoxib (Bextra) 2004 US Risk of heart attack and stroke.<br \/>\nVincamine 1987 Germany Hematologic toxicity.<br \/>\nXenazoic acid 1965 France Hepatotoxicity.<br \/>\nXimelagatran (Exanta) 2006 Germany Hepatotoxicity<br \/>\nZimelidine 1983 Worldwide Risk of Guillain\u2013Barr\u00e9 syndrome, hypersensitivity reaction, hepatotoxicity] banned worldwide.<br \/>\nZomepirac 1983 UK, Germany, Spain, US Anaphylactic reactions and non-fatal allergic reactions, renal failure<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Shared from a friend on Facebook&#8230; As the vaccine worshippers keep claiming &#8220;science says so&#8221; and proceed to try and shut down or discredit people by throwing around phrases like &#8220;I believe Science over Google&#8221; (a search engine to access the world&#8217;s largest library by the way) I thought this would interest them. Below is &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.tomgrimshaw.com\/tomsblog\/?p=17314\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Science Got It Wrong&#8221;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5,6,133],"tags":[],"class_list":["post-17314","post","type-post","status-publish","format-standard","hentry","category-general-interest","category-health-tips","category-vaccines"],"_links":{"self":[{"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=\/wp\/v2\/posts\/17314","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=17314"}],"version-history":[{"count":2,"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=\/wp\/v2\/posts\/17314\/revisions"}],"predecessor-version":[{"id":50879,"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=\/wp\/v2\/posts\/17314\/revisions\/50879"}],"wp:attachment":[{"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=17314"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=17314"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.tomgrimshaw.com\/tomsblog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=17314"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}